Description

Digoxin-Phosphatidylethanolamine Conjugate is a specialized biochemical conjugate designed for advanced pharmaceutical research and development. This compound is engineered to enhance the targeted delivery and therapeutic efficacy of the cardiac glycoside digoxin by linking it to a phosphatidylethanolamine moiety. It is a critical intermediate for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those focused on novel drug delivery systems, liposomal formulations, and targeted cancer therapies. The precise conjugation offers a pathway to improve pharmacokinetic profiles and reduce off-target effects.

Application

• Liposomal Drug Delivery Systems: A key component in the development of liposome-based carriers for targeted delivery of cardiac therapeutics.
• Pharmaceutical R&D: Serves as a critical intermediate in the synthesis of novel prodrugs and antibody-drug conjugates (ADCs) for oncology.
• Cardiovascular Research: Used in preclinical studies to investigate improved delivery mechanisms for digoxin and related cardiac agents.
• Bioconjugation Studies: Acts as a model compound for studying the chemistry and efficacy of drug-phospholipid conjugates.
• Nanomedicine Development: Incorporated into nanoparticle formulations to enhance solubility and bioavailability of hydrophobic drug molecules.

Basic Information

Product Name	Digoxin-Phosphatidylethanolamine Conjugate
CAS No.	129966-52-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Digoxin-PE Conjugate; Digoxin Phosphatidylethanolamine; Digoxin linked to PE; 3β-[(O-2,6-Dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12β,14-dihydroxy-5β-card-20(22)-enolide Conjugate with Phosphatidylethanolamine; Cardiac Glycoside-Phospholipid Conjugate
EINECS	Contact for details

Quality Control

Our Digoxin-Phosphatidylethanolamine Conjugate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store unopened vials at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. For short-term use, the material may be stored at 2-8°C for up to one week. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solvent Residue (GC)	Meets ICH guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.