Description

D-Ins(1,4,5)P3, 3Li is a high-purity lithium salt of the inositol phosphate derivative, D-myo-inositol 1,4,5-trisphosphate. This compound is a critical second messenger analog used extensively in biochemical and pharmacological research to study intracellular calcium signaling pathways. It is an essential reagent for researchers in cell biology, neuroscience, and drug discovery who require precise and reliable tools to investigate receptor-mediated signal transduction. The product is supplied as a hygroscopic, light-sensitive solid, necessitating careful handling and storage.

Application

• Biochemical Research: As a standard and reference compound in studies of phosphoinositide signaling cascades and calcium mobilization from intracellular stores.
• Cell Biology: Used to investigate the role of IP3 receptors in cellular processes such as muscle contraction, neurotransmitter release, and cell proliferation.
• Neuroscience & Pharmacology: A key tool for characterizing and modulating IP3 receptor function in neuronal cells, aiding in the study of neurological disorders and the development of novel therapeutics.
• Enzyme Studies: Serves as a substrate or inhibitor for enzymes like phosphatases and kinases involved in inositol phosphate metabolism.
• Diagnostic Development: Potential use in the development of assay kits and diagnostic tools for measuring IP3 levels or receptor activity in biological samples.

Basic Information

Product Name	D-Ins(1,4,5)P3, 3Li
CAS No.	129828-69-9
Molecular Formula	C6H12Li3O15P3
Molecular Weight	468.00 g/mol
Synonyms	D-myo-Inositol 1,4,5-trisphosphate trilithium salt; Ins(1,4,5)P3 trilithium salt; IP3 trilithium salt; 1D-myo-Inositol 1,4,5-trisphosphate trilithium salt; D-IP3 Li salt; Inositol trisphosphate (1,4,5) trilithium salt; myo-Inositol 1,4,5-trisphosphate trilithium salt
EINECS	Contact for details

Quality Control

Our D-Ins(1,4,5)P3, 3Li is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity suitable for sensitive research applications. Each lot is analyzed with advanced techniques including HPLC and NMR to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. The product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep the primary container in a sealed secondary container with a suitable desiccant. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Biological Activity (Calcium Release)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.