Description

4-Isothiocyanatophenylaminothiocarbonyl-2-((2-Aminoethylaminocarbonylethyl)Phenylethylamino)-5'-n-Ethylcarboxamidoadenosine is a sophisticated, multi-functional adenosine derivative designed for advanced biochemical research and pharmaceutical development. This compound matters for its unique bifunctional reactive groups, which enable precise conjugation and labeling of biomolecules, facilitating critical studies in molecular biology and targeted drug discovery. It is primarily needed by research institutions, pharmaceutical R&D departments, and diagnostic kit manufacturers focused on developing novel assays, affinity probes, and targeted therapeutic agents.

Application

• Bioconjugation Reagent: Used for covalent attachment to proteins, antibodies, or oligonucleotides via its isothiocyanate and amine-reactive groups for creating targeted probes.
• Affinity Labeling: Serves as a key intermediate in the synthesis of affinity chromatography ligands for purifying adenosine-binding proteins.
• Pharmaceutical Intermediate: Acts as a critical building block in the research and development of novel adenosine receptor-targeted therapeutics.
• Diagnostic Probe Development: Utilized in the design of enzyme-linked immunosorbent assay (ELISA) components and other diagnostic detection systems.
• Biochemical Research: Enables the study of adenosine signaling pathways and receptor interactions through specific labeling techniques.
• Fluorescent Tag Precursor: Can be derivatized to create fluorescently labeled adenosine analogs for cellular imaging and flow cytometry.

Basic Information

Product Name	4-Isothiocyanatophenylaminothiocarbonyl-2-((2-Aminoethylaminocarbonylethyl)Phenylethylamino)-5'-n-Ethylcarboxamidoadenosine
CAS No.	129666-43-9
Molecular Formula	C₃₃H₄₀N₁₀O₄S₂
Molecular Weight	728.89 g/mol
Synonyms	5'-N-Ethylcarboxamidoadenosine, 2-[(2-Aminoethylcarbamoyl)ethyl]phenyl]ethyl-4-isothiocyanatophenylthiocarbamate derivative; N⁶-[4-[(2-Aminoethylcarbamoyl)ethyl]phenyl]ethyl-5'-(N-ethylcarboxamido)adenosine-2',3'-isothiocyanate; Bifunctional Adenosine Isothiocyanate Derivative; Adenosine Receptor Affinity Label; A2A Adenosine Receptor Probe Precursor; 2-[(2-Aminoethylcarbamoyl)ethyl]phenylethyl 4-Isothiocyanatophenylthiocarbamoyl-5'-N-ethylcarboxamidoadenosine
EINECS	Contact for details

Quality Control

Our 4-Isothiocyanatophenylaminothiocarbonyl-2-((2-Aminoethylaminocarbonylethyl)Phenylethylamino)-5'-n-Ethylcarboxamidoadenosine is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC purity analysis, mass spectrometry (MS) confirmation, and NMR structural verification. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider under an inert atmosphere to maintain stability. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.