Description

5-(n-(4-Azidobenzoyl)-3-Aminoallyl)Deoxyuridine 5'-Monophosphate is a specialized nucleotide analog modified with a photoreactive azido group, enabling its use as a critical cross-linking agent in molecular biology research. This compound matters for its ability to form covalent bonds upon UV irradiation, making it indispensable for studying nucleic acid-protein interactions and for the development of advanced diagnostic probes. It is primarily needed by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on genomics, proteomics, and the development of novel therapeutic and diagnostic platforms.

Application

• Photoaffinity Labeling: A key reagent for cross-linking and identifying biomolecular interactions, particularly between nucleic acids and proteins.
• Probe Development: Used in the synthesis of photoactivatable probes for diagnostic assays and genomic analysis.
• Structural Biology Studies: Employed to map binding sites and understand the three-dimensional structure of nucleic acid complexes.
• Bioconjugation Chemistry: Serves as a versatile building block for creating stable conjugates between oligonucleotides and other molecules (e.g., fluorophores, affinity tags).
• Antiviral & Anticancer Research: Investigated as a potential modified nucleotide for incorporation into oligonucleotides targeting viral replication or specific genetic pathways in oncology.
• Next-Generation Sequencing (NGS): Potential utility in developing novel sequencing chemistries or library preparation methods.

Basic Information

Product Name	5-(n-(4-Azidobenzoyl)-3-Aminoallyl)Deoxyuridine 5'-Monophosphate
CAS No.	129623-36-5
Molecular Formula	C20H21N6O10P
Molecular Weight	536.39 g/mol
Synonyms	5-[N-[3-[(4-Azidobenzoyl)amino]allyl]]-2'-deoxyuridine 5'-monophosphate; 5-(N-(4-Azidobenzoyl)-3-aminoallyl)dUMP; 5-(3-((4-Azidobenzamido)allyl)-2'-deoxyuridine 5'-monophosphate; Azido-dUMP; Photoactivatable dUMP; 5-AA-dUMP; 5-(N-(4-Azidobenzoyl)-3-aminoprop-2-en-1-yl)-2'-deoxyuridine-5'-monophosphate
EINECS	Contact for details

Quality Control

Our 5-(n-(4-Azidobenzoyl)-3-Aminoallyl)Deoxyuridine 5'-Monophosphate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment and spectroscopic methods for structural confirmation. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant for long-term stability. This compound is light-sensitive (store away from light) and should be handled under subdued lighting conditions. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 3.0%
Solubility	Soluble in DMSO, Methanol; Slightly soluble in Water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.