Description

2,4-Dinitrophenyl-Dioleoylphosphatidylethanolamine is a specialized, chemically modified phospholipid derivative. This compound is of significant value as a key intermediate and functionalized lipid in advanced biochemical and biophysical research. It is primarily required by research institutions and pharmaceutical developers working in areas such as membrane biophysics, targeted drug delivery systems, and the development of diagnostic assays. Its unique structure allows for specific conjugation and labeling applications within complex lipid matrices.

Application

• Liposome and Lipid Nanoparticle (LNP) Research: As a functionalized component for surface modification, targeting, or stability enhancement in drug delivery carrier development.
• Membrane Protein Studies: Used to create labeled or modified lipid bilayers for investigating protein-lipid interactions and membrane dynamics.
• Diagnostic Assay Development: Serves as a hapten-carrier conjugate or a critical reagent in the development of immunoassays and biosensors.
• Bioconjugation and Probe Synthesis: Acts as a versatile intermediate for attaching reporter molecules (e.g., fluorophores, quenchers) to lipid structures.
• Model Membrane Systems: Incorporated into artificial membranes (e.g., vesicles, supported bilayers) to study specific chemical or physical properties.
• Pharmaceutical R&D: Utilized in preclinical research for exploring novel lipid-based therapeutic formulations and delivery mechanisms.

Basic Information

Product Name	2,4-Dinitrophenyl-Dioleoylphosphatidylethanolamine
CAS No.	129509-47-3
Molecular Formula	C47H81N2O11P
Molecular Weight	881.13 g/mol
Synonyms	DOPE-DNP; DNP-DOPE; 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine-N-(2,4-dinitrophenyl); N-(2,4-Dinitrophenyl)-1,2-dioleoyl-sn-glycero-3-phosphoethanolamine; Dinitrophenylphosphatidylethanolamine; DNP-PE; 2,4-DNP-PE; Dinitrophenylated DOPE
EINECS	Contact for details

Quality Control

Our 2,4-Dinitrophenyl-Dioleoylphosphatidylethanolamine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency, meeting the exacting standards required for research and development applications. Certificates of Analysis (COA) detailing specifications such as purity (by HPLC), structural confirmation (by NMR/MS), and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange waxy solid or film
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Solubility	Soluble in chloroform, DMSO; sparingly soluble in ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.