Description

1,2,6,7-Tetrahydroxypyrrolizidine is a high-purity pyrrolizidine alkaloid derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical chiral building block and synthetic intermediate for the development of novel bioactive molecules. It is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry, process development, and the synthesis of complex natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of potential therapeutic agents and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and the design of new drug candidates targeting various biological pathways.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard for studying pyrrolizidine alkaloid metabolism and toxicity.
• Organic Synthesis: Serves as a versatile building block for constructing complex polyhydroxylated nitrogen heterocycles found in natural products.
• Process Development: Used in route scouting and optimization for the scalable production of fine chemicals and advanced intermediates.

Basic Information

Product Name	1,2,6,7-Tetrahydroxypyrrolizidine
CAS No.	129415-27-6
Molecular Formula	C7H13NO4
Molecular Weight	175.18 g/mol
Synonyms	(1R,2R,6R,7R)-1,2,6,7-Tetrahydroxypyrrolizidine; 1,2,6,7-Tetrahydroxyhexahydropyrrolizine; Alexine; Casuarine; Casuarin; Casuarinine; DAB 1; 1,2,6,7-Tetrahydroxy-pyrrolizidine
EINECS	Contact for details

Quality Control

Our 1,2,6,7-Tetrahydroxypyrrolizidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.