Description

Biotinylamidoethyl-3-(4-Hydroxy-3-Iodophenyl)Propionamide β-Sulfoxide is a specialized biotinylated chemical intermediate designed for advanced biochemical research and pharmaceutical development. This compound is critical for applications requiring high-affinity binding and precise molecular targeting due to its biotin-avidin system compatibility and reactive sulfoxide group. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel diagnostics, targeted drug delivery systems, and proteomics research tools.

Application

• Bioconjugation Reagent: Used for labeling antibodies, proteins, and peptides for use in immunoassays (ELISA, Western Blot) and flow cytometry.
• Targeted Drug Delivery: Serves as a key linker molecule in the synthesis of biotin-drug conjugates for site-specific therapeutic action.
• Diagnostic Probe Development: Essential for creating sensitive detection probes in molecular diagnostics and histochemistry.
• Affinity Chromatography: Immobilized on solid supports for the purification of biomolecules via streptavidin-biotin interaction.
• Cell Surface Labeling: Facilitates the tagging and visualization of cell surface receptors in live-cell imaging studies.
• Proteomics & Biomarker Discovery: Employed in pull-down assays and mass spectrometry to isolate and identify protein complexes.

Basic Information

Product Name	Biotinylamidoethyl-3-(4-Hydroxy-3-Iodophenyl)Propionamide β-Sulfoxide
CAS No.	129312-14-7
Molecular Formula	C22H31IN4O5S
Molecular Weight	614.47 g/mol
Synonyms	Biotin-HPDP Sulfoxide; Biotinylated HPDP Sulfoxide; N-[6-(Biotinamido)hexyl]-3'-(2'-pyridyldithio)propionamide Sulfoxide; Biotin-HPDP β-Sulfoxide; 3-(4-Hydroxy-3-iodophenyl)propionamidoethyl biotin sulfoxide; Biotinylamidoethyl-3-(4-hydroxy-3-iodophenyl)propionamide sulfoxide; Biotin HPDP Sulfoxide; EZ-Link Biotin-HPDP Sulfoxide (related trade name)
EINECS	Contact for details

Quality Control

Our Biotinylamidoethyl-3-(4-Hydroxy-3-Iodophenyl)Propionamide β-Sulfoxide is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines for the production of advanced pharmaceutical intermediates, ensuring traceability and reliability for critical development work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Conforms to ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.