Description

11-Hydroxyprogesterone 11-Glucuronide is a high-purity conjugated metabolite of 11-hydroxyprogesterone, formed via glucuronidation. This compound is of significant value as a critical reference standard and analytical reagent for research and diagnostic applications. It is primarily needed by pharmaceutical R&D laboratories, clinical research organizations, and manufacturers of in-vitro diagnostic kits for the precise quantification and study of steroid hormone metabolism.

Application

• Pharmaceutical Reference Standard: Used for the calibration and validation of analytical methods (HPLC, LC-MS/MS) in drug metabolism and pharmacokinetic (DMPK) studies.
• Clinical Research Biomarker: Serves as a key analyte in the development of assays for monitoring steroid hormone pathways and related endocrine disorders.
• Diagnostic Kit Manufacturing: An essential component in the production of immunoassays and mass spectrometry-based kits for clinical diagnostics.
• Biochemical Research: Employed in enzymatic studies to investigate the activity and specificity of UDP-glucuronosyltransferase (UGT) enzymes.
• Quality Control: Used as an internal standard in laboratories to ensure the accuracy and precision of steroid hormone analysis.

Basic Information

Product Name	11-Hydroxyprogesterone 11-Glucuronide
CAS No.	129238-72-8
Molecular Formula	C27H38O9
Molecular Weight	506.59 g/mol
Synonyms	11β-Hydroxyprogesterone 11-Glucuronide; 11β-Hydroxypregn-4-ene-3,20-dione 11-Glucuronide; 11-Hydroxyprogesterone Glucuronide; 11-OHP-Gluc; 11β-Hydroxyprogesterone β-D-Glucopyranosiduronic Acid; Pregn-4-ene-3,20-dione, 11,21-dihydroxy-, 11-(β-D-glucopyranosiduronate)
EINECS	Contact for details

Quality Control

Our 11-Hydroxyprogesterone 11-Glucuronide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and diagnostic use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.