Description

Biotinyl Cystamine CAS NO 128915-82-2 is a specialized biochemical reagent featuring a biotin moiety linked via a cleavable disulfide bond. This compound is critical for introducing biotin tags onto target molecules, enabling subsequent isolation or detection through the high-affinity biotin-streptavidin interaction. It is an essential tool for researchers and manufacturers in the life sciences, particularly for applications in proteomics, affinity purification, and diagnostic assay development.

Application

• Bioconjugation and Labeling: Used as a heterobifunctional crosslinker for introducing biotin tags onto proteins, antibodies, nucleic acids, and other biomolecules.
• Affinity Chromatography: Serves as a key reagent for immobilizing ligands onto solid supports via disulfide bonds, facilitating reversible purification processes.
• Diagnostic Assay Development: Employed in the fabrication of ELISA, lateral flow assays, and other biosensors for signal amplification and detection.
• Proteomics Research: Utilized in pull-down assays and mass spectrometry workflows to isolate and identify protein complexes and post-translational modifications.
• Drug Delivery Systems: Investigated for creating targeted delivery vehicles where the disulfide bond provides a cleavable linkage responsive to the intracellular reducing environment.
• Surface Functionalization: Applied to modify nanoparticles, chips, and other surfaces for creating biospecific interfaces in research and diagnostics.

Basic Information

Product Name	Biotinyl Cystamine
CAS No.	128915-82-2
Molecular Formula	C14H26N4O3S2
Molecular Weight	362.51 g/mol
Synonyms	N-Biotinylcystamine; Biotin-Cystamine; Biotinylated Cystamine; D-Biotinyl Cystamine; 5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-[2-(2-aminoethyl)disulfanyl]ethyl]pentanamide; Biotin SS Amine; Biotin Disulfide Amine; Biotin-HPDP
EINECS	Contact for details

Quality Control

Our Biotinyl Cystamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification, to ensure it meets the high standards required for research and diagnostic applications. A Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.