Description

Suc-Ala-Gly-Pro-Phe-Pna CAS NO 128802-77-7 is a synthetic peptide substrate designed for biochemical and pharmaceutical research. This compound is critical for studying enzyme kinetics and inhibition, particularly for proteases like chymotrypsin and elastase. It is an essential tool for researchers and developers in the fields of pharmaceutical development, diagnostic assay manufacturing, and academic biochemistry.

Application

• Protease Enzyme Assays: Primary substrate for kinetic studies and activity measurements of serine proteases.
• Drug Discovery Screening: Used in high-throughput screening (HTS) platforms to identify and characterize novel protease inhibitors.
• Biochemical Research: A key reagent for investigating protease specificity, mechanism of action, and catalytic efficiency.
• Diagnostic Kit Development: Employed in the formulation of colorimetric or fluorometric diagnostic tests for enzymatic activity.
• Quality Control in Biologics: Used to monitor and validate the activity of enzyme-based biopharmaceutical products.

Basic Information

Product Name	Suc-Ala-Gly-Pro-Phe-Pna
CAS No.	128802-77-7
Molecular Formula	C31H38N6O9
Molecular Weight	638.67 g/mol
Synonyms	N-Succinyl-Ala-Gly-Pro-Phe-p-nitroanilide; Suc-AAPF-pNA; Suc-Ala-Ala-Pro-Phe-pNA (common variant); Substrate for Chymotrypsin; Protease Substrate IV; N-Succinyl-L-alanyl-L-alanyl-L-prolyl-L-phenylalanine 4-nitroanilide (related IUPAC); AAPF-pNA; Suc-AAPF-pNA
EINECS	Contact for details

Quality Control

Our Suc-Ala-Gly-Pro-Phe-Pna is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and identity confirmation by spectroscopic methods. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.