Description

Suc-Ala-Lys-Pro-Phe-Pna CAS NO 128802-74-4 is a synthetic peptide substrate designed for high-precision biochemical research and diagnostic applications. This compound serves as a critical tool for studying enzyme kinetics and activity, particularly for proteases like chymotrypsin and related serine proteases. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic reagent sectors who require reliable, well-characterized substrates for assay development and quality control.

Application

• Enzyme Activity Assays: Primary substrate for the spectrophotometric determination of chymotrypsin and elastase activity.
• Biochemical Research: Used in kinetic studies to investigate protease specificity, inhibition, and catalytic mechanisms.
• Diagnostic Reagent Manufacturing: A key component in the formulation of clinical diagnostic kits for measuring pancreatic function and other protease-related biomarkers.
• Pharmaceutical Development: Employed in high-throughput screening (HTS) platforms to identify and characterize novel protease inhibitors as potential drug candidates.
• Quality Control: Used as a reference standard in QC laboratories to validate the performance of enzymatic assays and diagnostic equipment.

Basic Information

Product Name	Suc-Ala-Lys-Pro-Phe-Pna
CAS No.	128802-74-4
Molecular Formula	C₃₄H₄₆N₈O₁₀
Molecular Weight	726.78 g/mol
Synonyms	Suc-AKP-F-pNA; N-Succinyl-Ala-Lys-Pro-Phe-p-nitroanilide; Suc-Ala-Lys-Pro-Phe-pNA; N-Succinyl-Alanyl-Lysyl-Prolyl-Phenylalanyl p-Nitroanilide; Chymotrypsin Substrate I; Substrate for Chymotrypsin; Suc-AKP-F-pNA; Protease Substrate Suc-AKP-F-pNA
EINECS	Contact for details

Quality Control

Our Suc-Ala-Lys-Pro-Phe-Pna is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and identity confirmation by mass spectrometry (MS) and infrared spectroscopy (IR). We provide Certificates of Analysis (COA) with detailed specifications for purity, assay, and impurity profiles, ensuring compliance with research and in-vitro diagnostic (IVD) grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0% (on dried basis)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.