Description

2,6-Bis[(4R)-4-Phenyl-2-Oxazolinyl]Pyridine is a high-value, chiral ligand and building block in advanced organic synthesis. Its core value lies in its ability to induce stereoselectivity in catalytic reactions, which is critical for producing enantiomerically pure compounds. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require precise control over molecular chirality for the development of active ingredients and specialty materials.

Application

• As a chiral ligand in asymmetric catalysis, including hydrogenation, cyclopropanation, and Diels-Alder reactions.
• Key building block for the synthesis of complex pharmaceutical intermediates requiring high enantiomeric purity.
• Utilized in the research and development of novel agrochemicals and plant protection agents.
• Component in the preparation of advanced materials and metal-organic frameworks (MOFs) with specific chiral properties.
• Precursor for specialty catalysts used in academic and industrial R&D laboratories.
• Standard reference compound for analytical method development in chiral separation techniques (e.g., HPLC, SFC).

Basic Information

Product Name	2,6-Bis[(4R)-4-Phenyl-2-Oxazolinyl]Pyridine
CAS No.	128249-70-7
Molecular Formula	C23H19N3O2
Molecular Weight	369.42 g/mol
Synonyms	(R,R)-2,6-Bis(4-phenyl-4,5-dihydrooxazol-2-yl)pyridine; PyBOX Ligand; (R,R)-2,6-Bis(4-phenyl-2-oxazolin-2-yl)pyridine; (4R,4'R)-2,6-Bis(4-phenyl-4,5-dihydrooxazol-2-yl)pyridine; 2,6-Bis[(4R)-4-phenyl-4,5-dihydro-1,3-oxazol-2-yl]pyridine; (R,R)-Ph-PyBOX; Chiral Pyridine-bis(oxazoline) Ligand
EINECS	Contact for details

Quality Control

Our 2,6-Bis[(4R)-4-Phenyl-2-Oxazolinyl]Pyridine is manufactured under strict quality protocols to ensure high chemical and chiral purity, meeting the stringent requirements of research and process chemistry. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and key analytical data. We adhere to cGMP principles where applicable to support pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.