Description

1-Lauroyl-2-Stearoyl-sn-Glycero-3-Phosphocholine is a high-purity, synthetic phospholipid with a defined fatty acid chain composition, offering superior consistency for advanced research and formulation. This compound is critical for creating model membrane systems, such as liposomes and lipid bilayers, with specific biophysical properties. It is essential for researchers and developers in pharmaceuticals, biotechnology, and advanced material science who require precise lipid components for drug delivery, membrane studies, and diagnostic applications.

Application

• Liposome and Lipid Nanoparticle (LNP) Formulation: A key component for constructing stable, uniform vesicles for drug and gene delivery systems.
• Biophysical Membrane Research: Used to create defined model membranes for studying lipid-protein interactions, membrane fluidity, and permeability.
• Pharmaceutical Excipient: Serves as a functional lipid in advanced parenteral formulations to enhance stability and bioavailability.
• Diagnostic Reagent Development: Employed in the manufacture of reagents for clinical diagnostics and biosensors.
• Biomimetic Coatings: Utilized in surface engineering to create biocompatible, cell-membrane mimicking layers on medical devices and implants.
• Reference Standard: Acts as a high-purity analytical standard for quality control in lipid-based product manufacturing.

Basic Information

Product Name	1-Lauroyl-2-Stearoyl-sn-Glycero-3-Phosphocholine
CAS No.	127912-48-5
Molecular Formula	C43H86NO8P
Molecular Weight	776.11 g/mol
Synonyms	1-Lauroyl-2-stearoyl-sn-glycero-3-phosphocholine; 12:0-18:0 PC; LSPC; 1-Lauroyl-2-stearoyl-phosphatidylcholine; PC(12:0/18:0); Phosphatidylcholine (12:0/18:0); 1-Dodecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine
EINECS	Contact for details

Quality Control

Our 1-Lauroyl-2-Stearoyl-sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and formulation. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Fatty Acid Composition (GC)	Conforms to specified ratio (Lauroyl/Stearoyl)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.