Description

1-o-(n-Dabsyl-11-Amino-1-Undecyl)-2-o-Decanoylphosphatidylcholine is a specialized, synthetic phospholipid derivative designed for advanced research and development applications. This compound is highly valued for its unique structure, which incorporates a dabsyl chromophore and a reactive amino group, making it an essential tool for labeling, probing, and modifying lipid membranes. It is primarily utilized by researchers and product developers in the pharmaceutical, biotechnology, and diagnostic sectors. Its precise chemical architecture enables critical studies in membrane biophysics, targeted drug delivery systems, and the development of novel biosensors.

Application

• Fluorescent Labeling of Lipids and Membranes: The integrated dabsyl group serves as a fluorescent probe for tracking lipid dynamics, membrane fusion, and cellular uptake in model and biological systems.
• Development of Targeted Drug Delivery Vehicles: Used in the synthesis and functionalization of liposomes and lipid nanoparticles (LNPs) to create targeted carriers with surface-conjugated ligands.
• Bioconjugation and Protein-Lipid Interaction Studies: The reactive amino moiety allows for covalent attachment to proteins, peptides, or other biomolecules to study lipid-protein interactions.
• Biosensor and Diagnostic Assay Development: Acts as a key component in the fabrication of sensor layers for detecting specific analytes or enzymatic activities related to lipid metabolism.
• Basic Research in Membrane Biophysics: Employed to create asymmetric or functionalized model membranes for investigating phase behavior, permeability, and mechanical properties.
• Material Science for Bio-interfaces: Used to engineer surface coatings with specific biological functionalities for implants, lab-on-a-chip devices, and tissue engineering scaffolds.

Basic Information

Product Name	1-o-(n-Dabsyl-11-Amino-1-Undecyl)-2-o-Decanoylphosphatidylcholine
CAS No.	126942-42-5
Molecular Formula	C58H94N4O9P
Molecular Weight	1014.4 g/mol
Synonyms	Dabsyl PE; 1-Dabsyl-2-decanoyl-sn-glycero-3-phosphocholine; Dabsyl-labeled phosphatidylethanolamine analog; N-Dabsyl-1,2-didecanoyl-sn-glycero-3-phosphoethanolamine; 1-(N-Dabsylamino)undecyl-2-decanoyl-phosphatidylcholine; Dabsyl-C11-PC; Fluorescent phospholipid derivative; Amino-reactive dabsyl lipid
EINECS	Contact for details

Quality Control

Every batch of 1-o-(n-Dabsyl-11-Amino-1-Undecyl)-2-o-Decanoylphosphatidylcholine is produced and analyzed under strict quality protocols to ensure consistency and purity for sensitive research applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as purity, identity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This compound is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange solid or film
Identification (HPLC/MS)	Conforms to structure
Identification (IR)	Conforms to reference
Purity (HPLC)	≥ 95%
Assay (Titration)	≥ 97%
Solubility	Soluble in chloroform, DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.