Description

L-Carnitine-D9 is a stable isotope-labeled analog of L-Carnitine, where nine hydrogen atoms are replaced by deuterium, making it an essential internal standard for precise quantitative analysis. This high-purity compound is critical for ensuring accuracy and reliability in mass spectrometry-based research and quality control protocols. It is primarily utilized by analytical laboratories, pharmaceutical R&D teams, and clinical research organizations involved in metabolomics, pharmacokinetic studies, and nutritional biomarker analysis.

Application

• Mass Spectrometry Internal Standard: Serves as a critical reference compound for the accurate quantification of endogenous L-Carnitine in biological samples (e.g., plasma, urine, tissue) using LC-MS/MS and GC-MS.
• Pharmacokinetic & Drug Metabolism Studies: Used as a stable isotope tracer to study the absorption, distribution, metabolism, and excretion (ADME) of carnitine and related compounds.
• Clinical Diagnostics & Biomarker Research: Enables precise measurement of carnitine levels for research into metabolic disorders, such as primary and secondary carnitine deficiencies.
• Nutritional & Sports Science Research: Facilitates the accurate analysis of carnitine supplementation effects on muscle metabolism and energy production in research settings.
• Pharmaceutical Quality Control: Employed in the assay and impurity profiling of L-Carnitine active pharmaceutical ingredients (APIs) and finished drug products to meet regulatory standards.
• Metabolomics and Proteomics: A key tool in high-throughput screening and discovery workflows for identifying and quantifying metabolites in complex biological systems.

Basic Information

Product Name	L-Carnitine-D9
CAS No.	126827-79-0
Molecular Formula	C7H6D9NO3
Molecular Weight	167.23 g/mol (for C7H6D9NO3)
Synonyms	(3R)-3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium-1,1,2,2,3,3,4,4,4-d9 Inner Salt; Vitamin Bt-d9; Levocarnitine-d9; L(-)-Carnitine-d9; (R)-3-Carboxy-2-hydroxypropyl)trimethylammonium-d9 Hydroxide Inner Salt; Carnitine-d9 (L-form); L-Carnitine (methyl-d9); Deuterated L-Carnitine
EINECS	Contact for details

Quality Control

Our L-Carnitine-D9 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ²H, ¹³C) for isotopic enrichment and structural confirmation, and HPLC for chemical and isotopic purity assessment. We provide comprehensive Certificates of Analysis (COA) detailing batch-specific results for identity, assay, deuterium enrichment, and related substances. Our quality commitment ensures the material meets the high standards required for sensitive analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Deuterium Enrichment	≥ 98 atom % D
Isotopic Purity (HPLC)	≥ 98%
Chemical Purity (HPLC)	≥ 98%
Specific Rotation	-29° to -32° (c=1 in H2O)
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.