Description

4,4-Dicarboxy-5-(Pyridoxyl-5'-Phosphate)Proline is a specialized, high-purity biochemical derivative that serves as a critical intermediate and research standard. This compound matters for its role in advanced biochemical synthesis, particularly in the development of enzyme inhibitors and probes for studying vitamin B6-dependent processes. It is primarily needed by pharmaceutical R&D teams, diagnostic reagent manufacturers, and academic researchers focused on metabolic pathways and coenzyme chemistry.

Application

• Pharmaceutical Intermediate: Synthesis of novel enzyme inhibitors and targeted therapeutic agents.
• Biochemical Research: As a standard or probe in studies of pyridoxal phosphate-dependent enzymes and transamination reactions.
• Diagnostic Reagent Manufacturing: Key component in the development of enzymatic assay kits for clinical diagnostics.
• Metabolite Analysis: Reference standard in LC-MS or HPLC methods for quantifying related metabolic pathways.
• Nutritional Science Research: Investigating the biochemical roles and interactions of vitamin B6 derivatives.

Basic Information

Product Name	4,4-Dicarboxy-5-(Pyridoxyl-5'-Phosphate)Proline
CAS No.	126706-34-1
Molecular Formula	C16H19N2O12P
Molecular Weight	462.30 g/mol
Synonyms	5-(Pyridoxyl-5'-phosphate)proline-4,4-dicarboxylic acid; PLP-Proline derivative; Pyridoxal phosphate proline analog; Vitamin B6-Proline conjugate; 4,4-Dicarboxy-5-(pyridoxal 5'-phosphate)proline; Proline-PLP adduct; 126706-34-1; 5-(3-Hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinyl)-1,3-dioxo-1,3,3a,4,6,6a-hexahydro-2H-cyclopenta[c]pyrrole-4,4-dicarboxylic acid 5-(dihydrogen phosphate)
EINECS	Contact for details

Quality Control

Our 4,4-Dicarboxy-5-(Pyridoxyl-5'-Phosphate)Proline is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to ambient conditions or light should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.