Description

4-Methylumbelliferyl3-Deoxy-D-Glycero-A-D-Galacto-2-Nonulosonicacid is a specialized fluorogenic substrate designed for the sensitive detection and quantification of sialidase (neuraminidase) enzyme activity. This compound matters because it provides a reliable, high-throughput method for enzymatic research and diagnostic assay development, offering a clear fluorescent signal upon enzymatic cleavage. It is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and diagnostic industries who require precise tools for studying carbohydrate-active enzymes, viral neuraminidases, and related biochemical pathways.

Application

• Enzymatic Assay Substrate: Primary use as a fluorogenic substrate for the detection and kinetic analysis of sialidase (neuraminidase) enzymes.
• Diagnostic Development: A key component in the development of fluorescent diagnostic kits for bacterial or viral infections involving sialidase activity.
• Biochemical Research: Used in research laboratories to study glycosidase mechanisms, carbohydrate metabolism, and cell surface glycan remodeling.
• Pharmaceutical Screening: Employed in high-throughput screening (HTS) platforms to identify and characterize potential neuraminidase inhibitor drugs.
• Microbiology Studies: Applied in assays to detect and characterize sialidase-producing microorganisms.
• Quality Control Reagent: Serves as a critical reference standard and reagent in the quality control of enzyme preparations and diagnostic products.

Basic Information

Product Name	4-Methylumbelliferyl3-Deoxy-D-Glycero-A-D-Galacto-2-Nonulosonicacid
CAS No.	126695-26-9
Molecular Formula	C19H23NO12
Molecular Weight	457.39 g/mol
Synonyms	4-Methylumbelliferyl α-KDN; 4-MU-α-KDN; 4-Methylumbelliferyl 3-deoxy-D-glycero-D-galacto-non-2-ulopyranosonic acid; 4-MU-3-deoxy-D-glycero-D-galacto-nonulosonic acid; Fluorogenic KDN substrate; α-KDN-4-methylumbelliferyl; Neuraminidase fluorogenic substrate (KDN type); 3-Deoxy-D-glycero-D-galacto-non-2-ulopyranosonic acid 4-methylumbelliferyl ester
EINECS	Contact for details

Quality Control

Our 4-Methylumbelliferyl3-Deoxy-D-Glycero-A-D-Galacto-2-Nonulosonicacid is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research and diagnostic applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0% (on dried basis)
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water
Functional Activity	Suitable for sialidase/neuraminidase assays

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.