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N6-(6-Amino)Hexyl-Atp (Biotin) CAS NO 126320-25-0
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CAS No.:126320-25-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
N6-(6-Amino)Hexyl-Atp (Biotin) is a biotinylated adenosine triphosphate (ATP) analog, a critical biochemical reagent for labeling and detection. This compound is engineered to provide a high-affinity handle for streptavidin/avidin binding, enabling the sensitive study of ATP-dependent processes. It is essential for researchers and manufacturers in life sciences, molecular diagnostics, and pharmaceutical development who require precise tools for kinase assays, nucleotide-protein interaction studies, and affinity purification.
Application
- Kinase Activity Assays: Used as a substrate or probe in high-throughput screening (HTS) to study kinase function and for inhibitor discovery.
- Affinity Purification & Pull-Down Assays: Facilitates the isolation and identification of ATP-binding proteins and their complexes via streptavidin-biotin interaction.
- Molecular Diagnostics: Serves as a key component in the development of sensitive detection kits for enzymatic activities and biomarkers.
- Bioconjugation & Probe Synthesis: Acts as a building block for creating labeled nucleotides used in imaging, biosensors, and microarray technologies.
- ATPase & Motor Protein Studies: Essential for investigating the mechanics and energy transduction of ATP-dependent enzymes like helicases and molecular motors.
- Drug Discovery Research: Employed in target validation and mechanistic studies for diseases involving dysregulated kinase or ATPase activity.
Basic Information
| Product Name | N6-(6-Amino)Hexyl-Atp (Biotin) |
| CAS No. | 126320-25-0 |
| Molecular Formula | C21H35N8O13P3S |
| Molecular Weight | 732.5 g/mol |
| Synonyms | Biotin-ATP; Biotinylated Adenosine 5'-Triphosphate; N6-(6-Aminohexyl)-ATP-Biotin; ATP-Biotin Conjugate; Biotin-ATP, N6-(6-Aminohexyl)adenosine-5'-triphosphate; Adenosine 5'-triphosphate, N6-(6-aminohexyl)-, biotin-labeled; Biotin-ATP analog; N6-(6-AHA)-ATP-Biotin |
| EINECS | Contact for details |
Quality Control
Our N6-(6-Amino)Hexyl-Atp (Biotin) is produced under stringent conditions to ensure batch-to-batch consistency and high biological activity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and functional assays to confirm biotin incorporation and activity. A detailed Certificate of Analysis (COA) documenting identity, purity, and performance is provided with every shipment to support your quality assurance protocols.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, keep desiccated at -20°C.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder or solid |
| Identification (HPLC/MS) | Conforms to reference standard |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 5.0 % |
| Functional Activity (Enzymatic Assay) | Conforms to standard |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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