Description

B-Lactosyl-1,1’-n-Hexacosanoyl-2’-Hexacosamide-4’-Octadecene-1’,3’-Diol (Synonym: B-Laccer) is a complex, high-purity synthetic glycosphingolipid, a critical building block in advanced biochemical research and development. This compound is essential for studying cell membrane structure, signal transduction pathways, and receptor-ligand interactions due to its specific lactosyl head group and long-chain ceramide backbone. It is primarily utilized by research institutions and pharmaceutical companies focused on immunology, oncology, and the development of novel therapeutic agents and diagnostic tools.

Application

• Biochemical Research: As a standard or substrate for investigating glycosphingolipid metabolism, cell adhesion, and recognition processes.
• Pharmaceutical Development: For use in drug discovery programs targeting cancer cell surfaces, immune modulation, and infectious diseases.
• Diagnostic Reagent Synthesis: Serving as a key intermediate in the production of high-specificity assay components and biomarkers.
• Membrane Biophysics Studies: Utilized in model membrane systems (e.g., liposomes, lipid rafts) to study membrane fluidity and organization.
• Glycobiology: A crucial tool for enzymology studies involving glycosyltransferases and glycosidases.
• Reference Standard: For quality control and analytical method development in laboratories requiring certified reference materials.

Basic Information

Item	Detail
Product Name	B-Lactosyl-1,1’-n-Hexacosanoyl-2’-Hexacosamide-4’-Octadecene-1’,3’-Diol
CAS No.	125712-73-4
Molecular Formula	C80H155NO13
Molecular Weight	1282.13 g/mol
Synonyms	B-Laccer; Lactosylceramide (Bovine, β-form); β-D-Galactosyl-(1→4)-β-D-glucosylceramide; D-Glucose, O-β-D-galactopyranosyl-(1→4)-O-β-D-glucopyranosyl-(1↔1)-N-(hexacosanoyl)-2-amino-4-octadecene-1,3-diol; Glycosphingolipid Gb3 (isoform B); CD77 Antigen (B isoform); Ceramide dibexoside; Globotriaosylceramide analog.
EINECS	Contact for details

Quality Control

Every batch of B-Lactosyl-1,1’-n-Hexacosanoyl-2’-Hexacosamide-4’-Octadecene-1’,3’-Diol is manufactured and analyzed under strict quality management systems. We guarantee high purity and batch-to-batch consistency through comprehensive analytical techniques including NMR, HPLC, and mass spectrometry. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profiles is supplied with each shipment to ensure it meets the exacting standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, containers should be sealed under an inert atmosphere (e.g., argon or nitrogen) and kept in a desiccated environment to maintain stability and purity. Allow the sealed vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.