Description

Udp-2-Acetamido-2-Deoxygalacturonic Acid CAS NO 125710-37-4 is a key nucleotide sugar derivative, specifically a uridine diphosphate N-acetylgalactosamine analog, essential for glycosylation research and biosynthesis pathways. This compound serves as a vital biochemical tool and a high-purity building block for the enzymatic synthesis of complex carbohydrates and glycoconjugates. It is primarily required by research institutions, pharmaceutical developers, and biotechnology companies focused on glycobiology, enzymology, and the development of novel therapeutic agents.

Application

• Glycosyltransferase Substrate: Acts as a critical donor substrate for enzymes like GalNAc-transferases in the study of O-linked glycosylation.
• Glycoconjugate Synthesis: Used in the enzymatic and chemoenzymatic synthesis of oligosaccharides, glycopeptides, and glycolipids for research and development.
• Biochemical Research: Essential for investigating carbohydrate metabolism, enzyme kinetics, and the biosynthesis of glycosaminoglycans (GAGs).
• Pharmaceutical Development: Serves as a precursor or intermediate in the development of carbohydrate-based drugs, vaccines, and diagnostics.
• Enzyme Characterization: Utilized to assay, purify, and characterize the activity of specific glycosyltransferases in vitro.
• Metabolic Pathway Studies: A key reagent for probing and modulating nucleotide sugar metabolism in cellular systems.

Basic Information

Product Name	Udp-2-Acetamido-2-Deoxygalacturonic Acid
CAS No.	125710-37-4
Molecular Formula	C17H25N3O17P2
Molecular Weight	605.33 g/mol
Synonyms	UDP-2-Acetamido-2-deoxygalacturonic acid; UDP-GalNAcA; Uridine 5'-(trihydrogen diphosphate), P'→5'-ester with 2-(acetylamino)-2-deoxy-α-D-galactopyranuronic acid; UDP-N-acetyl-α-D-galactosaminuronic acid; UDP-α-D-GalNAcA; Uridine diphosphate N-acetylgalactosaminuronic acid
EINECS	Contact for details

Quality Control

Our Udp-2-Acetamido-2-Deoxygalacturonic Acid is produced under stringent quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for sensitive biochemical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 90% (by UV)
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.