Description

Glycero-3-Phosphoinositol 4-Phosphate is a key phosphorylated inositol derivative and a crucial intermediate in the biosynthesis of higher phosphoinositides, which are essential signaling molecules in eukaryotic cells. This compound matters for researchers and developers as it enables the study and manipulation of intracellular signaling pathways related to cell growth, metabolism, and vesicular trafficking. It is primarily needed by the life science research, pharmaceutical development, and biotechnology sectors for biochemical research, enzyme substrate studies, and as a precursor in the synthesis of more complex phosphoinositides.

Application

• Biochemical Research: Used as a critical substrate and intermediate to study phosphoinositide kinases, phosphatases, and phospholipases.
• Cell Signaling Studies: Essential for investigating the role of phosphoinositides in cellular processes like membrane trafficking, cytoskeletal reorganization, and signal transduction.
• Enzyme Assay Development: Serves as a standard or substrate in high-throughput screening assays for drug discovery targeting lipid kinases and related enzymes.
• Pharmaceutical R&D: Acts as a precursor in the synthesis of labeled (e.g., radioactive or fluorescent) phosphoinositides for advanced metabolic and imaging studies.
• Academic Research: Fundamental tool for universities and research institutes exploring lipid biochemistry and cell biology.
• Diagnostic Reagent Manufacturing: Potential use in developing components for diagnostic kits that measure specific enzyme activities or lipid metabolites.

Basic Information

Product Name	Glycero-3-Phosphoinositol 4-Phosphate
CAS No.	125638-70-2
Molecular Formula	C9H18O14P2
Molecular Weight	436.17 g/mol
Synonyms	GroPIns4P; Glycerophosphoinositol 4-phosphate; 1-(sn-Glycero-3-phospho)-1D-myo-inositol 4-phosphate; sn-Glycero-3-phospho-1D-myo-inositol 4-phosphate; GPI 4-P; 1D-myo-Inositol, 1-(sn-glycero-3-phospho)-, 4-(dihydrogen phosphate); Glycerylphosphorylinositol 4-phosphate; L-α-Glycerophosphorylinositol 4-phosphate
EINECS	Contact for details

Quality Control

Our Glycero-3-Phosphoinositol 4-Phosphate is produced under stringent quality management protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is characterized using advanced analytical techniques including NMR and mass spectrometry for structural confirmation. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider storage under an inert atmosphere. Allow the product to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water, methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.