Description

Azidobenzamidotaurocholate is a chemically modified bile acid derivative, specifically designed as a research-grade biochemical tool. This compound is of significant value for its utility as a photoaffinity labeling agent and a molecular probe in transporter and receptor studies. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies engaged in advanced studies of hepatic transport systems, protein-ligand interactions, and drug discovery.

Application

• Photoaffinity Labeling: Used to covalently tag and identify bile acid transporters (e.g., NTCP, ASBT) and binding proteins in biological membranes.
• Molecular Probe Development: Serves as a critical tool for investigating the structure, function, and kinetics of hepatobiliary transport mechanisms.
• Drug Discovery Research: Employed in high-throughput screening assays to identify and characterize novel modulators of bile acid pathways.
• Biochemical Mechanism Studies: Facilitates the study of protein-ligand interactions and the mapping of active sites on target proteins.
• Diagnostic Agent Research: Investigated for potential use in developing targeted imaging agents for liver function and disease.

Basic Information

Product Name	Azidobenzamidotaurocholate
CAS No.	125378-99-6
Molecular Formula	C33H48N6O7S
Molecular Weight	672.84 g/mol
Synonyms	7α,12α-Dihydroxy-3α-(ω-azido-p-benzamido)-5β-cholan-24-oyltaurine; N-(4-Azidobenzoyl)taurocholic Acid; Azido-Taurocholic Acid Benzamide; Photoactivatable Taurocholate; ABAT; NTCP Photoaffinity Probe
EINECS	Contact for details

Quality Control

Our Azidobenzamidotaurocholate is produced under strict quality management protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and functional validation in relevant assay systems. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research integrity.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This compound is hygroscopic (moisture-sensitive) and light-sensitive. For long-term stability, store under inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, Methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.