Description

Uridine 5'-Diphosphate Bromoacetol is a specialized nucleotide derivative, a crucial biochemical tool for research and development. This compound serves as a key intermediate in enzymatic studies and the synthesis of modified nucleotides, enabling precise biochemical modifications. It is primarily utilized by researchers and manufacturers in the fields of pharmaceutical development, enzymology, and molecular biology for probing enzyme mechanisms and creating novel biomolecules.

Application

• Enzymology Research: Acts as a substrate or inhibitor analog for studying glycosyltransferases and other nucleotide-dependent enzymes.
• Bioconjugation & Labeling: Serves as a reactive intermediate for the site-specific labeling of proteins, nucleic acids, or other biomolecules via its bromoacetol moiety.
• Nucleotide Synthesis: Used as a key building block in the chemical and enzymatic synthesis of novel or modified uridine diphosphate (UDP) sugars and other nucleotide conjugates.
• Glycobiology Studies: Essential for investigating carbohydrate-active enzymes (CAZymes) involved in polysaccharide biosynthesis and modification.
• Pharmaceutical Intermediate: Employed in the research and development stages of creating nucleotide-based therapeutics and diagnostic agents.
• Biochemical Probe Development: Utilized to create affinity probes for target identification and validation in drug discovery pipelines.

Basic Information

Product Name	Uridine 5'-Diphosphate Bromoacetol
CAS No.	125303-05-1
Molecular Formula	C16H21BrN2O16P2
Molecular Weight	639.19 g/mol
Synonyms	UDP-Bromoacetol; 5'-UDP-Bromoacetol; Uridine 5'-(trihydrogen diphosphate) P'→5'-ester with 3-bromo-2-oxopropyl β-D-glucopyranosiduronic acid; Bromoacetol UDP; UDP-3-bromo-2-oxopropyl glucuronate; UDP-β-D-glucuronate bromoacetol ester
EINECS	Contact for details

Quality Control

Our Uridine 5'-Diphosphate Bromoacetol is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.