Description

1'-Hydroxykainic Acid is a specialized kainoid compound, a derivative of the potent neuroexcitatory amino acid kainic acid. This molecule is of significant interest in neuroscience research due to its structural relationship to kainate receptor agonists, serving as a valuable biochemical tool for studying glutamate receptor subtypes and neuropharmacology. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in neurological disorder research and drug discovery.

Application

• Neuroscience Research: Acts as a key reference standard and biochemical probe for investigating the function and pharmacology of kainate-type glutamate receptors.
• Neuropharmacology Studies: Used in the study of excitotoxicity, synaptic plasticity, and the development of novel therapeutic agents for neurological conditions.
• Biochemical Assay Development: Serves as a critical component in developing and validating in vitro assays for receptor binding and enzyme inhibition studies.
• Pharmaceutical R&D: Employed as an intermediate or reference compound in the discovery and development of central nervous system (CNS) targeted drugs.
• Academic Research: Utilized in university and institutional labs for fundamental research on ionotropic glutamate receptors and their role in brain function and disease.

Basic Information

Product Name	1'-Hydroxykainic Acid
CAS No.	125292-93-5
Molecular Formula	C10H15NO6
Molecular Weight	245.23 g/mol
Synonyms	(2S,3S,4S)-3-(Carboxymethyl)-4-(1-hydroxyprop-1-en-2-yl)pyrrolidine-2-carboxylic acid; 1'-OH-Kainic Acid; 1'-Hydroxykainate; 2-Carboxy-3-carboxymethyl-4-isopropenylpyrrolidine-3-acetic acid 1'-ol
EINECS	Contact for details

Quality Control

Our 1'-Hydroxykainic Acid is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.