Description

Caged Atp, Disodium Salt is a chemically modified, photolabile derivative of adenosine triphosphate (ATP) designed for precise, light-triggered release of the bioactive molecule. This compound matters as a critical research tool for studying fast, localized biochemical signaling events in real-time, enabling unparalleled temporal and spatial control in experimental systems. It is primarily needed by researchers and developers in the fields of cell biology, neuroscience, and enzymology for applications such as photolysis experiments, caged compound studies, and the investigation of rapid ATP-dependent processes.

Application

• Photolysis and Uncaging Experiments: Used as a "caged" precursor for the light-induced release of ATP to study rapid signaling kinetics in biological systems.
• Cellular Physiology Research: Enables the investigation of ATP-gated ion channels (P2X receptors) and other purinergic signaling pathways with precise temporal control.
• Enzymology Studies: Serves as a substrate for studying the kinetics and mechanisms of ATP-dependent enzymes (kinases, ATPases, synthases) upon photoactivation.
• Neuroscience and Muscle Research: Applied in studies of neurotransmitter release, synaptic plasticity, and muscle contraction mechanisms triggered by localized ATP pulses.
• Biophysical Probes: Utilized in the development of advanced imaging and sensing techniques to map ATP distribution and flux in live cells and tissues.
• Drug Discovery Screening: Acts as a tool compound in high-throughput assays targeting purinergic receptors and ATP-utilizing proteins.

Basic Information

Product Name	Caged Atp, Disodium Salt
CAS No.	125229-58-5
Molecular Formula	C18H22N5O16P3Na2 (or similar, based on caging group)
Molecular Weight	Contact for details
Synonyms	P3-[1-(2-Nitrophenyl)ethyl] Adenosine 5'-Triphosphate, Disodium Salt; caged-ATP; NPE-caged ATP; 2-Nitrophenylethyl-caged ATP; Adenosine 5'-triphosphate, P3-[1-(2-nitrophenyl)ethyl] ester, disodium salt; Photoactivatable ATP; "Caged" Adenosine Triphosphate Disodium Salt
EINECS	Contact for details

Quality Control

Our Caged Atp, Disodium Salt is produced and handled under strict quality protocols to ensure batch-to-batch consistency and high chemical purity for research applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to meet the exacting standards required for photolysis and biochemical studies. Certificates of Analysis (COA) detailing specific test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is strictly light-sensitive (protect from all light exposure) and hygroscopic (moisture-sensitive). For long-term stability, store under inert atmosphere or vacuum desiccation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/UV)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Area Percent)
Water Content (KF)	≤ 3.0 %
Photolytic Efficiency	Contact for details
Solubility	Soluble in aqueous buffer solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.