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1-Behenoyl-2-Hydroxy-Sn-Glycero-3-Phosphocholine CAS NO 125146-65-8
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CAS No.:125146-65-8
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1-Behenoyl-2-Hydroxy-Sn-Glycero-3-Phosphocholine is a synthetic, high-purity lysophospholipid, specifically a lysophosphatidylcholine (LPC) derivative with a behenoyl (C22:0) fatty acid chain. This compound is a critical research-grade biochemical used to study membrane biophysics, lipid signaling pathways, and as a precursor in the synthesis of more complex phospholipids. It is essential for scientists and manufacturers in pharmaceutical R&D, lipidomics, and advanced drug delivery system development, particularly for creating liposomal formulations.
Application
- Lipidomics Research & Biomarker Discovery: Used as a standard or reference compound in mass spectrometry-based lipid analysis to identify and quantify lipid species in biological samples.
- Membrane Biophysics Studies: Serves as a model lipid to investigate the properties and behavior of lipid bilayers, membrane fluidity, and lipid-protein interactions.
- Pharmaceutical Excipient & Drug Delivery: A key component in the formulation of liposomes, niosomes, and other lipid nanoparticles for targeted and sustained release of active pharmaceutical ingredients (APIs).
- Biochemical Reagent: Acts as a substrate or intermediate in enzymatic assays and the chemical synthesis of more complex phospholipids like phosphatidylcholines.
- Cell Culture & Signaling Research: Utilized to study the role of lysophosphatidylcholines in cellular processes, including inflammation, apoptosis, and cell proliferation.
Basic Information
| Item | Details |
|---|---|
| Product Name | 1-Behenoyl-2-Hydroxy-Sn-Glycero-3-Phosphocholine |
| CAS No. | 125146-65-8 |
| Molecular Formula | C30H60NO8P |
| Molecular Weight | 593.78 g/mol |
| Synonyms | Lysophosphatidylcholine (22:0/0:0); LPC(22:0); 1-Docosanoyl-2-hydroxy-sn-glycero-3-phosphocholine; Behenoyl Lysophosphatidylcholine; LysoPC(22:0); sn-Glycero-3-phosphocholine, 1-behenoyl-2-hydroxy-; 2-Hydroxy-1-docosanoyl-sn-glycero-3-phosphocholine |
| EINECS | Contact for details |
Quality Control
Our high-purity biochemicals are manufactured under controlled conditions and undergo rigorous analytical testing. Each batch is supplied with a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Quality is assured through techniques including HPLC, NMR, and mass spectrometry to meet the stringent requirements of research and pharmaceutical development.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid or waxy solid |
| Identification (HPLC/MS) | Conforms to reference standard |
| Purity (HPLC) | ≥ 95% (Area %) |
| Assay (NMR) | ≥ 98% |
| Water Content (KF) | ≤ 1.0 % |
| Solvent Residue (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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