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1-Behenoyl-2-Hydroxy-Sn-Glycero-3-Phosphocholine CAS NO 125146-65-8


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CAS No.:125146-65-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-Behenoyl-2-Hydroxy-Sn-Glycero-3-Phosphocholine is a synthetic, high-purity lysophospholipid, specifically a lysophosphatidylcholine (LPC) derivative with a behenoyl (C22:0) fatty acid chain. This compound is a critical research-grade biochemical used to study membrane biophysics, lipid signaling pathways, and as a precursor in the synthesis of more complex phospholipids. It is essential for scientists and manufacturers in pharmaceutical R&D, lipidomics, and advanced drug delivery system development, particularly for creating liposomal formulations.

Application

  • Lipidomics Research & Biomarker Discovery: Used as a standard or reference compound in mass spectrometry-based lipid analysis to identify and quantify lipid species in biological samples.
  • Membrane Biophysics Studies: Serves as a model lipid to investigate the properties and behavior of lipid bilayers, membrane fluidity, and lipid-protein interactions.
  • Pharmaceutical Excipient & Drug Delivery: A key component in the formulation of liposomes, niosomes, and other lipid nanoparticles for targeted and sustained release of active pharmaceutical ingredients (APIs).
  • Biochemical Reagent: Acts as a substrate or intermediate in enzymatic assays and the chemical synthesis of more complex phospholipids like phosphatidylcholines.
  • Cell Culture & Signaling Research: Utilized to study the role of lysophosphatidylcholines in cellular processes, including inflammation, apoptosis, and cell proliferation.

Basic Information

Item Details
Product Name 1-Behenoyl-2-Hydroxy-Sn-Glycero-3-Phosphocholine
CAS No. 125146-65-8
Molecular Formula C30H60NO8P
Molecular Weight 593.78 g/mol
Synonyms Lysophosphatidylcholine (22:0/0:0); LPC(22:0); 1-Docosanoyl-2-hydroxy-sn-glycero-3-phosphocholine; Behenoyl Lysophosphatidylcholine; LysoPC(22:0); sn-Glycero-3-phosphocholine, 1-behenoyl-2-hydroxy-; 2-Hydroxy-1-docosanoyl-sn-glycero-3-phosphocholine
EINECS Contact for details

Quality Control

Our high-purity biochemicals are manufactured under controlled conditions and undergo rigorous analytical testing. Each batch is supplied with a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Quality is assured through techniques including HPLC, NMR, and mass spectrometry to meet the stringent requirements of research and pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to minimize condensation.

Specification

Item Specification
Appearance White to off-white solid or waxy solid
Identification (HPLC/MS) Conforms to reference standard
Purity (HPLC) ≥ 95% (Area %)
Assay (NMR) ≥ 98%
Water Content (KF) ≤ 1.0 %
Solvent Residue (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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