Description

2-Tolylacetyl-Coenzyme A is a specialized biochemical reagent and a key intermediate in the study of enzymatic pathways, particularly those involving acyl-CoA synthetases and transferases. This compound matters for researchers and industrial biochemists as it provides a critical tool for investigating metabolic processes, enzyme kinetics, and substrate specificity. It is primarily needed by professionals in pharmaceutical R&D, academic biochemistry laboratories, and biotechnology companies focused on metabolic engineering and drug discovery.

Application

• Enzymology Research: Used as a substrate to study the activity and mechanism of acyl-CoA utilizing enzymes.
• Metabolic Pathway Analysis: A crucial intermediate for probing biosynthetic and catabolic routes involving aromatic compounds.
• Pharmaceutical Development: Serves as a building block or probe in the discovery of enzyme inhibitors targeting metabolic diseases.
• Biochemical Assay Standard: Employed as a reference standard in quantitative assays (e.g., HPLC, MS) to measure enzyme activity or metabolite levels.
• Biocatalyst Screening: Used in high-throughput screening platforms to identify novel enzymes with activity towards tolylacetyl substrates.
• Academic Teaching & Training: A valuable compound for advanced biochemistry and molecular biology education.

Basic Information

Product Name	2-Tolylacetyl-Coenzyme A
CAS No.	124924-91-0
Molecular Formula	C32H48N7O17P3S
Molecular Weight	927.73 g/mol
Synonyms	2-Methylbenzeneacetyl-CoA; o-Tolylacetyl-Coenzyme A; 2-Methylphenylacetyl-Coenzyme A; CoA S-(2-Methylphenyl)acetate; (o-Tolylacetyl)CoA; 2-Tolylacetyl-CoA; o-Methylbenzeneacetyl-CoA; Acyl-Coenzyme A Derivative (2-Tolylacetyl)
EINECS	Contact for details

Quality Control

Our 2-Tolylacetyl-Coenzyme A is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC purity analysis, NMR confirmation, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and stability data.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, keep under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 3.0%
Solubility	Soluble in water, methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.