Description

2-Methyl-1,2-Di-o-Hexadecylglycerophosphocholine is a synthetic, high-purity phospholipid analog, specifically a methylated phosphatidylcholine derivative with two long C16 (hexadecyl) alkyl chains. This compound is of significant value for its role as a key intermediate and functional component in advanced lipid-based formulations and biomembrane research. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced material science sectors for developing liposomal drug delivery systems, creating synthetic membrane models, and studying lipid-protein interactions.

Application

• Liposomal Drug Delivery: A critical component for formulating stable, long-circulating liposomes for targeted and sustained release of therapeutic agents.
• Biomembrane Research: Used to create synthetic lipid bilayers and vesicles (e.g., giant unilamellar vesicles) for studying membrane biophysics, permeability, and protein insertion.
• Cell Biology & Biochemistry: Serves as a substrate or modulator in enzymatic studies and as a tool to investigate cellular signaling pathways involving phospholipids.
• Advanced Material Science: Employed in the fabrication of lipid nanoparticles (LNPs) for mRNA and gene therapy applications, and in the development of biosensors.
• Cosmetic & Dermal Formulations: Incorporated into high-end cosmetic products as a skin-identical lipid to enhance skin barrier function and delivery of active ingredients.
• Diagnostic Reagents: Used in the preparation of standards and reagents for clinical diagnostics and analytical chemistry.

Basic Information

Product Name	2-Methyl-1,2-Di-o-Hexadecylglycerophosphocholine
CAS No.	124771-01-3
Molecular Formula	C₄₂H₈₆NO₆P
Molecular Weight	732.10 g/mol
Synonyms	1,2-Di-O-hexadecyl-3-O-(2-methoxy-2-oxoethyl)-sn-glycerophosphocholine; 2-Methyl-1,2-dihexadecylglycerophosphocholine; Methyl-DHPC; Phosphatidylcholine, 2-methyl-1,2-dihexadecyl-; 1,2-Dihexadecyl-3-O-(2-methoxy-2-oxoethyl)-sn-glycero-3-phosphocholine; PC(16:0/16:0-Me); Synthetic methylated phospholipid
EINECS	Contact for details

Quality Control

Our 2-Methyl-1,2-Di-o-Hexadecylglycerophosphocholine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and formulation. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white waxy solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.