Description

n-(L-Leucyl)-2-Aminoacridone is a specialized amino acid-derivatized acridone compound, primarily used as a key intermediate and fluorescent labeling reagent in advanced biochemical research. Its value lies in its ability to act as a sensitive probe for detecting and quantifying amino acids, peptides, and proteins, enabling critical analysis in proteomics and diagnostic assay development. This high-purity biochemical is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors who require reliable, high-performance reagents for analytical and diagnostic applications.

Application

• Fluorescent Labeling Reagent: Used for the sensitive detection and quantification of amino acids, peptides, and proteins in HPLC and capillary electrophoresis.
• Proteomics Research: Serves as a critical derivatization agent for peptide mapping, protein sequencing, and post-translational modification analysis.
• Diagnostic Assay Development: Employed in the synthesis of fluorescent probes and conjugates for clinical diagnostics and immunoassays.
• Biochemical Synthesis: Acts as a key building block for synthesizing more complex fluorescent tags and molecular probes.
• Pharmaceutical Analysis: Utilized in quality control and analytical method development for peptide-based pharmaceuticals.
• Enzyme Activity Studies: Applied in assays designed to monitor protease and peptidase activity through fluorescence-based detection.

Basic Information

Product Name	n-(L-Leucyl)-2-Aminoacridone
CAS No.	124689-91-4
Molecular Formula	C22H23N3O2
Molecular Weight	361.44 g/mol
Synonyms	2-Aminoacridone-L-leucine conjugate; L-Leucyl-2-aminoacridone; N-(L-Leucyl)-2-aminoacridone; 2-AA-Leu; Acridone-9-carboxylic acid, 2-amino-, L-leucinamide; Fluorescent leucine derivative; Leucine-acridone probe; AAD-Leu
EINECS	Contact for details

Quality Control

Our n-(L-Leucyl)-2-Aminoacridone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and analytical applications. Each lot undergoes comprehensive analysis, including identity confirmation by spectroscopic methods and purity assessment by HPLC. A Certificate of Analysis (COA) detailing specific results for identity, assay, and related substances is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.