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4-Methylumbelliferyl2-Acetamido-3,4,6-Tri-o-Acetyl-2-Deoxy-B-D-Galactopyranoside CAS NO 124167-46-0


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CAS No.:124167-46-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Methylumbelliferyl2-Acetamido-3,4,6-Tri-o-Acetyl-2-Deoxy-B-D-Galactopyranoside is a specialized fluorogenic substrate designed for the sensitive detection and quantification of specific glycosidase enzyme activity. This compound is critical for researchers and quality control laboratories requiring precise enzymatic assays in biochemical and diagnostic applications. It is primarily utilized in life science research, pharmaceutical development, and diagnostic kit manufacturing for studying carbohydrate metabolism and related enzymatic pathways.

Application

  • Enzymatic Assay Substrate: A key fluorogenic substrate for the detection and kinetic study of β-N-acetylhexosaminidases and related glycosidases.
  • Biochemical Research: Used in fundamental research to investigate enzyme mechanisms, inhibition, and carbohydrate-active enzyme (CAZyme) function.
  • Diagnostic Development: Employed in the development of fluorometric diagnostic tests and kits for lysosomal storage disorders, such as Tay-Sachs and Sandhoff diseases.
  • Pharmaceutical Screening: Utilized in high-throughput screening (HTS) platforms to identify potential therapeutic inhibitors or activators of target glycosidases.
  • Microbiology: Applied in studies of bacterial glycosidases for microbiological identification and characterization.
  • Quality Control (QC): Serves as a reference standard or critical reagent in QC laboratories for enzyme purity and activity testing.

Basic Information

Product Name 4-Methylumbelliferyl2-Acetamido-3,4,6-Tri-o-Acetyl-2-Deoxy-B-D-Galactopyranoside
CAS No. 124167-46-0
Molecular Formula C24H27NO13
Molecular Weight 537.47 g/mol
Synonyms 4-MU-β-D-GalNAc-3,4,6-triacetate; 4-Methylumbelliferyl N-acetyl-β-D-galactosaminide triacetate; 4-Methylumbelliferyl 2-acetamido-2-deoxy-β-D-galactopyranoside-3,4,6-triacetate; 4-MU-β-GalNAc-3,4,6-TriAc; Fluorogenic β-N-acetylgalactosaminidase substrate; GalNAc-β-4MU triacetate; 2-Acetamido-2-deoxy-β-D-galactopyranoside 4-methylumbelliferyl ester 3,4,6-triacetate
EINECS Contact for details

Quality Control

Our 4-Methylumbelliferyl2-Acetamido-3,4,6-Tri-o-Acetyl-2-Deoxy-B-D-Galactopyranoside is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency suitable for sensitive research and diagnostic applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and performance in standard enzymatic assays. We adhere to relevant quality guidelines to support our global customer base in pharmaceutical and diagnostic development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC/MS) Conforms
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Specific Rotation Contact for details
Fluorogenic Activity Conforms to reference standard
Solubility Soluble in DMSO, DMF; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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