Description

Glycol Chitosan is a water-soluble derivative of chitosan, created by the covalent attachment of glycolic acid groups to the chitosan backbone. This modification significantly enhances its solubility in neutral and alkaline aqueous environments compared to native chitosan, unlocking a wider range of industrial and biomedical applications. It is a versatile biopolymer sought after by manufacturers in the pharmaceutical, cosmetic, and advanced materials sectors for its biocompatibility, film-forming ability, and mucoadhesive properties.

Application

• Pharmaceutical Drug Delivery: As a key excipient in nasal, ocular, and oral formulations for its mucoadhesive properties, enhancing drug residence time and bioavailability.
• Cosmetic & Personal Care: Used in skincare products, hair conditioners, and creams as a natural film-forming agent, moisturizer, and viscosity enhancer.
• Biomedical Engineering: Serves as a scaffold material in tissue engineering and wound healing dressings due to its biocompatibility and structural properties.
• Gene Delivery & Transfection: Functions as a non-viral vector for DNA and siRNA delivery in research and therapeutic applications, forming stable polyplexes.
• Food & Nutraceutical Encapsulation: Employed to create protective coatings for sensitive ingredients, enabling controlled release and improved stability.
• Agricultural Technology: Utilized in seed coatings and as a component in controlled-release systems for agrochemicals.

Basic Information

Product Name	Glycol Chitosan
CAS No.	123938-86-3
Molecular Formula	(C8H13NO5)n • (C2H4O)x
Molecular Weight	Variable (Polymer)
Synonyms	Chitosan glycolate; Glycolic acid chitosan ester; O-Carboxymethyl chitosan (partially substituted); Hydroxyacetyl chitosan; Poly(D-glucosamine-co-N-glycolyl-D-glucosamine); Water-soluble chitosan derivative; Chitosan hydroxyacetate
EINECS	Contact for details

Quality Control

Our Glycol Chitosan is produced under a strict quality management system. Each batch is tested to ensure consistent performance, including parameters such as degree of substitution, viscosity, and purity. Certificates of Analysis (COA) documenting these specifications are provided with every shipment. We can support compliance requirements for cGMP, ISO, and other relevant quality standards based on customer needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent moisture absorption, which can affect physical properties.

Specification

Item	Specification
Appearance	White to off-white powder or flakes
Identification (IR)	Conforms
Assay (as Glycol Chitosan)	≥ 95.0%
Degree of Substitution	0.2 - 1.0 (Customizable)
Viscosity (1% solution)	10 - 500 mPa·s (Customizable)
pH (1% solution)	4.0 - 7.0
Loss on Drying	≤ 10.0 %
Residue on Ignition	≤ 1.0 %
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.