Description

Trinitrophenylglutamyllysine CAS NO 123774-73-2 is a specialized synthetic peptide derivative, primarily recognized for its role as a key intermediate in advanced biochemical research and pharmaceutical development. Its unique structure, incorporating a trinitrophenyl (TNP) group, makes it a valuable tool for studying protein-protein interactions, enzyme kinetics, and as a hapten in immunology. This compound is essential for researchers and manufacturers in the fields of bioconjugation, diagnostic reagent development, and immunochemical studies. Its precise synthesis and high purity are critical for ensuring reproducible and reliable experimental outcomes.

Application

• Biochemical Research: Used as a hapten-carrier conjugate for antibody production and immunological assays.
• Diagnostic Development: Serves as a critical intermediate in the synthesis of enzyme-linked immunosorbent assay (ELISA) components and other diagnostic markers.
• Pharmaceutical Intermediates: Acts as a building block in the research and development of novel peptide-based therapeutics and targeted drug delivery systems.
• Protein Labeling & Detection: Employed in techniques for labeling proteins and studying ligand-receptor binding due to the spectroscopic properties of the TNP group.
• Enzyme Inhibition Studies: Utilized as a substrate analog or inhibitor in enzymatic research to probe active sites and mechanisms.
• Academic & Institutional Research: Fundamental reagent for universities and research institutes conducting studies in biochemistry, molecular biology, and immunology.

Basic Information

Product Name	Trinitrophenylglutamyllysine
CAS No.	123774-73-2
Molecular Formula	C20H27N5O10
Molecular Weight	497.46 g/mol
Synonyms	N6-(2,4,6-Trinitrophenyl)-L-lysyl-L-glutamic Acid; TNP-ε-Lys-Glu; L-Glutamic Acid, N6-(2,4,6-trinitrophenyl)-L-lysyl-; Trinitrophenyl-Lys-Glu; (2S)-2-[[(2S)-6-[(2,4,6-Trinitrophenyl)amino]-2-aminohexanoyl]amino]pentanedioic Acid; H-Lys(TNP)-Glu-OH; ε-TNP-L-lysyl-L-glutamic Acid
EINECS	Contact for details

Quality Control

Our Trinitrophenylglutamyllysine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing including HPLC for purity, mass spectrometry for identity confirmation, and chiral purity analysis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines where applicable for the production of this high-value biochemical intermediate.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive). For long-term storage, desiccate and keep under inert atmosphere. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.