Description

7-(4-Oxobutyl)Guanine is a high-purity, modified nucleobase derivative of guanine, featuring a reactive 4-oxobutyl side chain. This functionalization makes it a valuable intermediate for advanced organic synthesis and pharmaceutical research, particularly in the development of nucleoside analogs and targeted molecular probes. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors seeking to develop novel therapeutic agents or diagnostic tools.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel nucleoside analog drugs, including potential antiviral and anticancer agents.
• Bioconjugation & Probe Development: The reactive ketone group enables site-specific conjugation to antibodies, peptides, or other biomolecules for creating targeted diagnostic probes.
• Chemical Biology Research: Used in studying enzyme mechanisms, nucleic acid interactions, and cellular processes involving purine metabolism.
• Fine Chemical Synthesis: Serves as a specialized precursor for synthesizing complex organic molecules with specific biological activity.
• Academic & R&D Laboratories: Employed in fundamental research to explore new chemical entities and their biochemical properties.

Basic Information

Product Name	7-(4-Oxobutyl)Guanine
CAS No.	123752-07-8
Molecular Formula	C9H11N5O2
Molecular Weight	221.22 g/mol
Synonyms	7-(4-Oxobutyl)guanine; 9H-Guanine, 7-(4-oxobutyl)-; 4-(2-Amino-6-oxo-1,6-dihydro-9H-purin-7-yl)butanal; 7-(4-Oxobutyl)-1H-purin-6-amine; Guanine, 7-(4-oxobutyl)-; 7-(4-Oxobutyl)-9H-guanine; 7-(4-Oxobutyl)-1,9-dihydro-6H-purin-6-one
EINECS	Contact for details

Quality Control

Our 7-(4-Oxobutyl)Guanine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.