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n-Myristoyl-D-Erythro-Sphingosine CAS NO 123408-74-2


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CAS No.:123408-74-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-Myristoyl-D-Erythro-Sphingosine is a high-purity, synthetic sphingolipid derivative, specifically a C14 fatty acid-conjugated ceramide. This compound is a critical biochemical tool and intermediate for advanced life science research and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the fields of lipidomics, cell signaling studies, and the formulation of novel therapeutic agents targeting metabolic and neurological pathways.

Application

  • Biochemical Research: A key standard and substrate for studying sphingolipid metabolism, ceramide-mediated apoptosis, and cell membrane dynamics.
  • Pharmaceutical R&D: Serves as a crucial intermediate in the synthesis of more complex sphingolipids and potential drug candidates for cancer, inflammation, and skin barrier disorders.
  • Lipidomics & Analytical Standards: Used as a certified reference material (CRM) for the accurate quantification and identification of ceramide species in biological samples via LC-MS/MS.
  • Cosmeceutical Development: Employed in the formulation of high-end skincare products aimed at restoring the skin's natural lipid barrier and improving hydration.
  • Cell Culture & Signaling Studies: Applied in vitro to investigate the role of specific ceramide species in signal transduction pathways and cellular stress responses.

Basic Information

Product Name n-Myristoyl-D-Erythro-Sphingosine
CAS No. 123408-74-2
Molecular Formula C32H63NO3
Molecular Weight 509.86 g/mol
Synonyms N-Tetradecanoylsphingosine; C14-Ceramide (d18:1/14:0); D-erythro-C14-Ceramide; (2S,3R,4E)-2-Tetradecanoylamino-4-octadecene-1,3-diol; Ceramide (d18:1/14:0); N-Myristoyl-D-erythro-sphingosine; Sphingosine, N-myristoyl-D-erythro-; Tetradecanoyl sphingosine
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Quality Control

Our n-Myristoyl-D-Erythro-Sphingosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for structural confirmation, and NMR for identity verification, to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. Allow the product to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture absorption.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (MS) Conforms to structure
Purity (HPLC) ≥ 98.0%
Loss on Drying ≤ 1.0%
Residue on Ignition ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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