Description

1 2-Dimyristoyl-Sn-Glycero-3-Phosphoetha is a high-purity synthetic phospholipid, specifically a phosphatidylethanolamine (PE) derivative with defined myristoyl chains. This compound is a critical building block in the formulation of advanced lipid-based delivery systems and biomimetic membranes. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors requiring precise lipid composition for consistent, reproducible results.

Application

• Liposome & Nanoparticle Formulation: A key structural component for creating stable liposomal drug delivery vehicles and lipid nanoparticles (LNPs) for mRNA and siRNA therapeutics.
• Biomembrane Research: Used in the construction of model membranes, supported lipid bilayers (SLBs), and vesicles for studying membrane biophysics, protein-lipid interactions, and cellular processes.
• Cell Culture & Transfection Reagents: Incorporated into lipid mixtures to enhance the efficiency of transfection reagents for introducing nucleic acids into cells.
• Diagnostic Assays: Serves as a substrate or membrane component in diagnostic kits and biosensor development.
• Cosmetic & Dermal Delivery: Employed in high-end cosmetic formulations as an emulsifier and penetration enhancer for active ingredients.
• Bioconjugation & Probe Synthesis: Provides a reactive amine group (from the phosphoethanolamine head) for coupling with fluorescent dyes, targeting ligands, or other molecules.

Basic Information

Product Name	1 2-Dimyristoyl-Sn-Glycero-3-Phosphoetha
CAS No.	123402-48-2
Molecular Formula	C33H66NO8P
Molecular Weight	635.85 g/mol
Synonyms	DMPE; 1,2-Dimyristoyl-sn-glycero-3-phosphoethanolamine; DMPE (14:0/14:0); PE(14:0/14:0); Phosphatidylethanolamine (14:0); 1,2-Ditetradecanoyl-sn-glycero-3-phosphoethanolamine; (2R)-2,3-Bis(tetradecanoyloxy)propyl 2-aminoethyl hydrogen phosphate; DMPE Lipid
EINECS	Contact for details

Quality Control

Our 1 2-Dimyristoyl-Sn-Glycero-3-Phosphoetha is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and structural confirmation by NMR and MS, to ensure it meets the stringent requirements for research and cGMP-grade applications. Certificates of Analysis (COA) with full traceability are provided.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation and hydrolysis. The product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a desiccator before opening to avoid condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.