Description

n-6,o-2'-Dibutyryladenosine 3':5'-Cyclic Monophosphate Sodium Salt 1H2O, 98% is a cell-permeable, hydrolysis-resistant analog of cyclic adenosine monophosphate (cAMP), widely used as a potent activator of protein kinase A (PKA) in biochemical and pharmacological research. This high-purity grade is essential for ensuring reliable and reproducible results in sensitive cell signaling studies. It is a critical research reagent for scientists in pharmaceutical R&D, academic institutions, and biotechnology companies investigating intracellular signal transduction pathways, gene expression, and metabolic regulation.

Application

• Biochemical Research: As a stable cAMP analog to study PKA-mediated signaling cascades and second messenger systems.
• Cell Biology Studies: For investigating the role of cAMP in cell differentiation, proliferation, and apoptosis in various cell lines.
• Pharmaceutical Screening: Used as a reference compound or tool molecule in drug discovery programs targeting G-protein-coupled receptors (GPCRs) and adenylate cyclase.
• Metabolic Research: To explore cAMP's effects on hormone action, glycogen metabolism, and lipolysis.
• Neuroscience Research: For studying synaptic plasticity, neuronal excitability, and long-term potentiation (LTP) where cAMP is a key modulator.

Basic Information

Product Name	n-6,o-2'-Dibutyryladenosine 3':5'-Cyclic Monophosphate Sodium Salt 1H2O, 98%
CAS No.	123334-06-5
Molecular Formula	C18H23N5NaO8P · H2O
Molecular Weight	529.38 g/mol (monohydrate)
Synonyms	Dibutyryl-cAMP sodium salt; db-cAMP sodium salt; N6,O2'-Dibutyryladenosine 3',5'-cyclic monophosphate sodium salt; Bu2cAMP sodium salt; Sodium N6,2'-O-dibutyryladenosine-3',5'-cyclic monophosphate; Adenosine 3',5'-cyclic monophosphate, N6,2'-O-dibutyryl-, sodium salt; 1H2O
EINECS	Contact for details

Quality Control

Our 98% purity grade is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent tests for residual solvents and moisture content. Certificates of Analysis (COA) with detailed chromatograms and full analytical data are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	3.0% - 5.0% (Theoretical for 1H2O: ~3.4%)
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.