Description

Corynanthine Hydrochloride is a high-purity alkaloid derivative used in advanced research and pharmaceutical development. This compound is valued for its specific pharmacological activity as a selective α-2 adrenergic receptor antagonist. It is primarily utilized by research institutions and pharmaceutical companies engaged in neuroscience, cardiovascular studies, and drug discovery programs. Our supply ensures consistent quality and reliable availability for critical global R&D and manufacturing processes.

Application

• Pharmacological Research: As a reference standard and active agent in studies targeting α-2 adrenergic receptors.
• Neuroscience Studies: For investigating autonomic nervous system function, neurotransmitter release, and related neurological pathways.
• Cardiovascular Research: Used in experimental models to study vascular tone, blood pressure regulation, and heart rate.
• Pharmaceutical Intermediate: Serves as a key building block or precursor in the synthesis of more complex therapeutic molecules.
• Biochemical Assay Development: Employed as a selective ligand in the development and validation of high-throughput screening (HTS) assays.
• Academic & Institutional R&D: Supports basic and applied research in university and government laboratory settings.

Basic Information

Product Name	Corynanthine Hydrochloride
CAS No.	123333-62-0
Molecular Formula	C21H26N2O3·HCl
Molecular Weight	390.90 g/mol
Synonyms	Corynanthine HCl; 17α-Hydroxyyohimban-16α-carboxylic acid methyl ester hydrochloride; Raubasine hydrochloride; α-Yohimbine hydrochloride; 3-Epi-α-yohimbine hydrochloride; (16α,17α)-17-Hydroxyyohimban-16-carboxylic acid methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our Corynanthine Hydrochloride is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and tests for residual solvents and heavy metals. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.