Description

4-Methylumbelliferyl3-Deoxy-D-Glycero-A-D-Galacto-2-Nonulosonicacidsodiumsalt is a specialized fluorogenic substrate used for the detection and quantification of sialidase (neuraminidase) enzyme activity. This compound matters for researchers and diagnostic manufacturers as it provides a highly sensitive and specific means to study viral infections, bacterial pathogens, and genetic disorders related to sialic acid metabolism. It is primarily needed by the life science research, in-vitro diagnostic (IVD), and pharmaceutical development sectors for enzymatic assays and high-throughput screening.

Application

• Sialidase (Neuraminidase) Activity Assays: A key substrate for fluorometric detection of enzyme activity in research and diagnostic kits.
• Virology Research: Used to study and screen for inhibitors of viral neuraminidases, such as those from influenza viruses.
• Bacteriology: Employed in assays to detect and characterize bacterial sialidases from pathogens like Clostridium perfringens and Vibrio cholerae.
• Genetic Disorder Studies: Applied in research on lysosomal storage diseases involving sialidase deficiencies.
• High-Throughput Screening (HTS): Utilized in drug discovery platforms to identify novel neuraminidase inhibitors.
• Diagnostic Kit Manufacturing: Serves as a critical raw material in the production of fluorogenic diagnostic tests for enzymatic activity.
• Biochemical Research: A tool for investigating the kinetics and specificity of sialidase enzymes in purified systems.

Basic Information

Product Name	4-Methylumbelliferyl3-Deoxy-D-Glycero-A-D-Galacto-2-Nonulosonicacidsodiumsalt
CAS No.	123269-95-4
Molecular Formula	C19H22NNaO12
Molecular Weight	479.37 g/mol
Synonyms	4-MU-3-deoxy-D-glycero-D-galacto-2-nonulosonic acid sodium salt; 4-Methylumbelliferyl-α-2,3-deoxy-N-acetylneuraminic acid sodium salt; 4-MU-α-2,3-deoxy-Neu5Ac sodium salt; Fluorogenic neuraminidase substrate; 4-MU-Neu5Ac2en Na salt; Sialidase substrate (4-MU labeled); 3-Deoxy-4-Methylumbelliferyl-N-acetylneuraminic acid sodium salt
EINECS	Contact for details

Quality Control

Our 4-Methylumbelliferyl3-Deoxy-D-Glycero-A-D-Galacto-2-Nonulosonicacidsodiumsalt is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for sensitive biochemical applications. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term stability, it is recommended to store desiccated under inert atmosphere. Allow the product to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details
Fluorogenic Activity	Functional in standard sialidase assay
Solubility	Soluble in water, DMSO, buffer solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.