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1-Myristoyl-Sn-Glycero-3-Phosphoethanolamine CAS NO 123060-40-2


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CAS No.:123060-40-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-Myristoyl-Sn-Glycero-3-Phosphoethanolamine is a high-purity, synthetic phospholipid, specifically a saturated phosphatidylethanolamine (PE) with a defined 14-carbon myristoyl chain. This compound is a critical building block for constructing biomimetic membranes and liposomal delivery systems, offering superior batch-to-batch consistency for research and formulation. It is essential for scientists and manufacturers in advanced pharmaceutical development, particularly for creating stable, targeted drug delivery vehicles and model membrane systems for biophysical studies.

Application

  • Liposome & Lipid Nanoparticle (LNP) Formulation: A key structural phospholipid for creating stable, uniform liposomes used in drug and vaccine delivery systems.
  • Biomimetic Membrane Research: Used to construct defined phospholipid bilayers for studying membrane protein interactions, permeability, and cell signaling mechanisms.
  • Diagnostic Reagent Preparation: Serves as a component in diagnostic kits and assays that require specific lipid environments or surface modifications.
  • Excipient in Advanced Therapeutics: Employed as a functional excipient to enhance the stability and efficacy of encapsulated active pharmaceutical ingredients (APIs).
  • Bioconjugation & Surface Functionalization: The primary amine group on the phosphoethanolamine headgroup provides a site for covalent attachment of targeting ligands, dyes, or other molecules.
  • Reference Standard & Analytical Chemistry: Used as a certified reference material in lipidomics research and for quality control in lipid-based product manufacturing.

Basic Information

Product Name 1-Myristoyl-Sn-Glycero-3-Phosphoethanolamine
CAS No. 123060-40-2
Molecular Formula C19H38NO8P
Molecular Weight 439.48 g/mol
Synonyms 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine; 14:0 Lyso PE; 1-Tetradecanoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine; Lyso PE(14:0/0:0); 1-Myristoyl-sn-glycerol-3-phosphoethanolamine; L-α-Lysophosphatidylethanolamine (C14:0); N/A; PE(14:0/0:0)
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Quality Control

Our 1-Myristoyl-Sn-Glycero-3-Phosphoethanolamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical and research applications. Certificates of Analysis (COA) detailing all specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This material is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to prevent condensation and moisture uptake.

Specification

Item Specification
Appearance White to off-white powder or solid
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 95.0%
Purity (TLC) Single spot
Solubility Soluble in chloroform, methanol; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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