Description

Azasetron Hydrochloride is a potent and selective 5-HT3 receptor antagonist. This compound is of significant interest in pharmaceutical research and development, particularly for its antiemetic properties. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in developing treatments for nausea and vomiting associated with chemotherapy, radiotherapy, and post-operative recovery.

Application

• Pharmaceutical Active Ingredient (API): Core component in the formulation of antiemetic medications.
• Oncology Supportive Care: Research and development of drugs to manage chemotherapy-induced nausea and vomiting (CINV).
• Postoperative Nausea and Vomiting (PONV) Prevention: Investigation for use in surgical and anesthetic recovery protocols.
• Radiotherapy-Induced Emesis Control: Potential application in mitigating side effects of radiation therapy.
• Biochemical Research: Used as a selective tool compound in pharmacological studies of serotonin (5-HT3) receptors.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in laboratories.

Basic Information

Product Name	Azasetron Hydrochloride
CAS No.	123040-96-0
Molecular Formula	C₁₇H₂₀N₄O₂·HCl
Molecular Weight	348.83 g/mol
Synonyms	Azasetron HCl; Y-25130; (±)-Azasetron Hydrochloride; N-[(1-Methyl-1H-indol-3-yl)carbonyl]-L-asparaginyl-1-azabicyclo[2.2.2]oct-3-ylamine Hydrochloride; 1-Azabicyclo[2.2.2]oct-3-ylamine, N-[(1-methyl-1H-indol-3-yl)carbonyl]-L-α-asparaginyl-, hydrochloride (1:1); Serotonin 5-HT3 Receptor Antagonist Y-25130
EINECS	Contact for details

Quality Control

Our Azasetron Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC, to ensure it meets stringent pharmaceutical-grade specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.