Description

Azasetron is a potent and selective serotonin 5-HT3 receptor antagonist. This compound is crucial for its antiemetic properties, effectively preventing nausea and vomiting. It is primarily needed by the pharmaceutical industry for the development of therapeutic agents, particularly in oncology and post-operative care.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced antiemetic drugs.
• Oncology Supportive Care: Research and development of medications to manage chemotherapy-induced nausea and vomiting (CINV).
• Post-Operative Nausea and Vomiting (PONV) Prevention: Used in formulating drugs aimed at preventing nausea following surgical procedures.
• Neuropharmacology Research: A valuable reference standard and tool compound for studying the 5-HT3 receptor pathway.
• Active Pharmaceutical Ingredient (API) Development: Serves as the core active component in finished dosage form development.
• Veterinary Medicine: Potential application in developing antiemetic treatments for animals.

Basic Information

Product Name	Azasetron
CAS No.	123040-95-9
Molecular Formula	C17H20N4O2
Molecular Weight	312.37 g/mol
Synonyms	Azasetron Hydrochloride; Y-25130; (±)-Azasetron; endo-N-(1-Azabicyclo[2.2.2]oct-3-yl)-6-chloro-3,4-dihydro-4-methyl-3-(methylsulfonyl)-2H-1,4-benzoxazine-8-carboxamide; 6-Chloro-3,4-dihydro-4-methyl-3-(methylsulfonyl)-N-(3-quinuclidinyl)-2H-1,4-benzoxazine-8-carboxamide; Y 25130; Y25130
EINECS	Contact for details

Quality Control

Our Azasetron is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets high-grade pharmaceutical standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.