Description

Azasetron is a potent and selective serotonin 5-HT3 receptor antagonist, identified by CAS No. 123040-93-7. This compound is of significant value in pharmaceutical research and development for its antiemetic properties, offering a targeted mechanism of action. It is primarily utilized by pharmaceutical companies and research institutions engaged in developing treatments for chemotherapy-induced nausea and vomiting (CINV) and other gastrointestinal disorders.

Application

• Pharmaceutical Intermediate: Key raw material in the synthesis of advanced antiemetic drug formulations.
• Research & Development: Used as a reference standard and active compound in preclinical studies for 5-HT3 receptor pharmacology.
• Oncology Supportive Care: Investigated for the prevention and treatment of nausea and vomiting associated with cancer chemotherapy.
• Gastrointestinal Disorder Research: Applied in studies targeting conditions like irritable bowel syndrome (IBS) and functional dyspepsia.
• Analytical Standard: Serves as a high-purity standard for quality control and method development in analytical laboratories (HPLC, LC-MS).
• Chemical Synthesis: Building block for creating novel chemical entities with potential therapeutic applications.

Basic Information

Product Name	Azasetron
CAS No.	123040-93-7
Molecular Formula	C17H20N4O2
Molecular Weight	312.37 g/mol
Synonyms	Azasetron Hydrochloride; Y-25130; (±)-Azasetron; N-[(1-Azabicyclo[2.2.2]oct-3-yl)-6-chloro-4-hydroxy-2-methyl-1H-indole-3-carboxamide]; 6-Chloro-4-hydroxy-N-(3-quinuclidinyl)-2-methyl-1H-indole-3-carboxamide; Y 25130; Y25130
EINECS	Contact for details

Quality Control

Our Azasetron is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC and other validated methods, to ensure it meets high-grade standards suitable for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.