Description

Azasetron Hydrochloride is a high-purity pharmaceutical intermediate and active ingredient, recognized for its role as a potent and selective 5-HT3 receptor antagonist. This compound is critical for ensuring the quality and efficacy of finished pharmaceutical products targeting specific therapeutic pathways. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development and production of antiemetic medications and neurological research.

Application

• Key intermediate in the synthesis of antiemetic pharmaceutical formulations.
• Active Pharmaceutical Ingredient (API) for 5-HT3 receptor antagonist drugs.
• Reference standard for analytical method development and quality control in pharmaceutical labs.
• Biochemical research tool for studying serotonin (5-HT) receptor function and signaling.
• Preclinical and clinical research material for investigating treatments for chemotherapy-induced nausea and vomiting (CINV).
• Starting material for the preparation of novel derivatives in medicinal chemistry programs.

Basic Information

Product Name	Azasetron Hydrochloride
CAS No.	123040-16-4
Molecular Formula	C₁₇H₂₀N₄O₂•HCl
Molecular Weight	348.83 g/mol
Synonyms	Azasetron HCl; Y-25130; (R)-5-(1-Azabicyclo[2.2.2]oct-3-yl)-3-(1H-indazol-3-yl)-4,5-dihydroisoxazol-5-ol Hydrochloride; 3-[(1R,3r,5S)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl] 1H-indazole-3-carboxylate Hydrochloride; Y 25130; Y25130
EINECS	Contact for details

Quality Control

Our Azasetron Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by spectroscopic methods, to ensure it meets stringent pharmaceutical-grade specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5% Any single impurity ≤0.5%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.