Description

S-(1,2-Dichloro-3,3,3-Trifluoro-1-Propenyl)Glutathione is a specialized glutathione conjugate, a key intermediate in the study of metabolic pathways and detoxification mechanisms. This compound is of significant interest for its role in the formation of reactive metabolites and its utility in biochemical research related to glutathione S-transferase activity. It is primarily sought by researchers and developers in the pharmaceutical, agrochemical, and toxicology sectors for use in analytical method development, metabolic profiling, and as a reference standard.

Application

• Biochemical Research: Used as a critical reference standard and intermediate in studies of glutathione conjugation pathways and xenobiotic metabolism.
• Pharmaceutical Development: Employed in the investigation of drug metabolism, specifically for identifying and characterizing reactive metabolites formed via glutathione adduction.
• Toxicology Studies: Serves as a model compound for understanding detoxification processes and bioactivation mechanisms of halogenated propenes.
• Analytical Chemistry: Utilized as a high-purity standard for calibrating instruments (e.g., LC-MS, HPLC) in method development for metabolite identification.
• Agrochemical Research: Applied in metabolic fate studies of fluorinated and chlorinated agrochemicals to assess environmental and biological interactions.

Basic Information

Product Name	S-(1,2-Dichloro-3,3,3-Trifluoro-1-Propenyl)Glutathione
CAS No.	122652-97-5
Molecular Formula	C₁₃H₁₇Cl₂F₃N₃O₆S
Molecular Weight	486.26 g/mol
Synonyms	Glutathione S-(1,2-dichloro-3,3,3-trifluoro-1-propenyl); S-(1,2-Dichloro-3,3,3-trifluoroprop-1-en-1-yl)glutathione; 1,2-Dichloro-3,3,3-trifluoro-1-propenyl glutathione conjugate; GST conjugate of 1,2-dichloro-3,3,3-trifluoropropene; L-Glutathione, S-(1,2-dichloro-3,3,3-trifluoro-1-propenyl)-; NSC 339586
EINECS	Contact for details

Quality Control

Our S-(1,2-Dichloro-3,3,3-Trifluoro-1-Propenyl)Glutathione is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, storage at -20°C is recommended. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.