Description

1-Naphthylacetylspermine is a specialized polyamine derivative that serves as a valuable biochemical tool and research compound. Its core value lies in its ability to interact with polyamine transport systems and metabolic pathways, making it a critical reagent for studying cell growth, proliferation, and apoptosis. This compound is primarily needed by researchers and developers in the fields of pharmaceutical R&D, oncology research, and molecular biology for investigating novel therapeutic targets.

Application

• Biochemical Research: Used as a substrate or inhibitor in studies of polyamine metabolism and transport mechanisms.
• Oncology & Cancer Research: Investigated for its potential effects on tumor cell growth and as a probe for understanding polyamine uptake in cancer cells.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the discovery of new polyamine-based therapeutics.
• Enzyme Studies: Employed in assays to study the activity of enzymes like spermidine/spermine N1-acetyltransferase (SSAT).
• Cell Culture & Physiology: Used to modulate intracellular polyamine levels and study their role in cellular processes.
• Academic Research: A vital compound for universities and research institutes focusing on cell signaling and metabolic pathways.

Basic Information

Product Name	1-Naphthylacetylspermine
CAS No.	122306-11-0
Molecular Formula	C23H33N5O
Molecular Weight	395.54 g/mol
Synonyms	N1-(1-Naphthylacetyl)spermine; N-(1-Naphthylacetyl)spermine; 1-Naphthaleneacetic acid spermine conjugate; N1-(1-Naphthylacetyl)-1,12-diamino-4,9-diazadodecane; Spermine, N-(1-naphthylacetyl)-; N1-(1-Naphthylacetyl)-4,9-diazadodecane-1,12-diamine
EINECS	Contact for details

Quality Control

Our 1-Naphthylacetylspermine is produced under a strict quality management system to ensure batch-to-batch consistency and high purity for research applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry for identity confirmation and purity verification. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.