Description

n-Heptadecanoyl-D-Erythro-Sphingosylphosphorylcholine is a high-purity, synthetic sphingolipid derivative, specifically a ceramide-1-phosphate analog with a defined C17:0 fatty acyl chain. This compound is a critical biochemical tool and a key intermediate in the study of sphingolipid metabolism and cell signaling pathways. It is essential for researchers and manufacturers in pharmaceutical development, lipidomics, and advanced biochemical research, where precise molecular structure and purity are paramount for reliable experimental and production outcomes.

Application

• Biochemical Research & Lipidomics: Serves as a high-purity standard for mass spectrometry, chromatography, and enzymatic assays to study sphingolipid biology, metabolism, and signaling.
• Pharmaceutical R&D: Used as a key intermediate or reference compound in the development of novel therapeutics targeting sphingolipid-related pathways, such as those involved in inflammation, apoptosis, and cancer.
• Cell Biology Studies: Applied in cell culture models to investigate the role of ceramide-1-phosphate analogs in cell proliferation, migration, and inflammatory responses.
• Enzyme Substrate/Inhibitor Studies: Acts as a specific substrate or inhibitor for enzymes like ceramide kinase (CERK) to elucidate their function and for high-throughput screening.
• Liposome & Drug Delivery System Formulation: Incorporated into lipid bilayers to modify membrane properties and create specialized liposomal carriers for targeted drug delivery.
• Diagnostic Reagent Development: Utilized in the formulation of calibrators and controls for diagnostic kits measuring sphingolipid levels in clinical samples.

Basic Information

Product Name	n-Heptadecanoyl-D-Erythro-Sphingosylphosphorylcholine
CAS No.	121999-64-2
Molecular Formula	C41H83N2O8P
Molecular Weight	763.08 g/mol
Synonyms	C17:0 Ceramide-1-Phosphate; Heptadecanoyl Sphingosylphosphorylcholine; N-Heptadecanoylsphingosine-1-Phosphocholine; D-erythro-Sphingosine, 1-(phosphonooxy)-N-(1-oxoheptadecyl)-, inner salt; Ceramide 1-Phosphate (C17:0); C17-Cer-1-P; C17 Ceramide Phosphocholine; N-Heptadecanoyl-D-erythro-sphingosylphosphorylcholine
EINECS	Contact for details

Quality Control

Every batch of n-Heptadecanoyl-D-Erythro-Sphingosylphosphorylcholine is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of research and development applications. Certificates of Analysis (COA) detailing lot-specific results from NMR, HPLC, and MS are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. The product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay	≥ 98% (by NMR)
Water Content (KF)	≤ 1.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.