Description

Desoxycorticosterone-7-Mercaptopropionic Acid is a key synthetic steroid derivative, specifically a corticosterone analog conjugated with a thiol-containing propionic acid moiety. This compound is of significant value as a versatile intermediate in the research and development of novel pharmaceutical agents, particularly in the fields of endocrinology and anti-inflammatory drug discovery. It is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of steroid-based therapeutics and biochemical probes.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel corticosteroid analogs and prodrugs with potential therapeutic applications.
• Biochemical Research: Used as a reference standard or a derivatization agent in analytical studies of steroid metabolism and hormone action.
• Drug Discovery: Serves as a precursor in medicinal chemistry programs aimed at developing new anti-inflammatory or immunosuppressive agents.
• Conjugation Chemistry: The mercaptopropionic acid side chain enables site-specific conjugation (e.g., to proteins, polymers, or solid supports) for creating targeted drug delivery systems or diagnostic tools.
• Academic & Contract Research: Utilized in university and CRO settings for fundamental research into adrenal steroid chemistry and receptor interactions.

Basic Information

Product Name	Desoxycorticosterone-7-Mercaptopropionic Acid
CAS No.	121748-46-7
Molecular Formula	C24H34O5S
Molecular Weight	434.59 g/mol
Synonyms	7α-Mercaptopropionic Acid Desoxycorticosterone; 21-Hydroxypregn-4-ene-3,20-dione 7α-(2-Mercaptopropanoate); DOC-7-MPA; 11-Deoxycorticosterone 7-Mercaptopropionate; Pregn-4-ene-3,20-dione, 21-hydroxy-7α-(2-mercaptopropanoate); Desoxycorticosterone 7α-(2-mercaptopropionate)
EINECS	Contact for details

Quality Control

Our Desoxycorticosterone-7-Mercaptopropionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and specific tests for related substances and residual solvents. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment to ensure full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Unknown Impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.