Description

(n-Acetylneuraminosyl-(2--8)-n-Glycolylneuraminic Acid)Gangliotetraosylceramide is a complex, biologically significant ganglioside, a class of glycosphingolipids found abundantly in nerve cell membranes. This high-purity compound is essential for advanced research into cell signaling, neural development, and receptor-ligand interactions. It is a critical reagent for pharmaceutical R&D, particularly in neuroscience, immunology, and the development of diagnostic tools and therapeutic agents targeting neurological disorders.

Application

• Neuroscience Research: Used as a standard or substrate in studies of neuronal cell adhesion, synaptic plasticity, and neurodegenerative disease mechanisms.
• Immunology & Vaccine Development: Serves as a target antigen in research for autoimmune diseases and in the design of conjugate vaccines against bacterial pathogens that mimic host gangliosides.
• Diagnostic Reagent Production: Employed in the development and calibration of immunoassays and biosensors for detecting ganglioside-related antibodies or biomarkers in clinical samples.
• Pharmaceutical R&D: Acts as a key intermediate or reference compound in drug discovery programs targeting cancer, bacterial toxins, and neurological conditions.
• Cell Biology Studies: Utilized to investigate the role of gangliosides in cell membrane structure, signal transduction, and apoptosis.
• Biochemical Standard: Provides a high-purity reference material for analytical method development, validation, and quality control in laboratories.

Basic Information

Product Name	(n-Acetylneuraminosyl-(2--8)-n-Glycolylneuraminic Acid)Gangliotetraosylceramide
CAS No.	121382-26-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	GD1a Ganglioside (with Neu5Gc); Disialoganglioside GD1a (Neu5Gc-containing); II3(Neu5Gc)2-Gg4Cer; Ganglioside GD1a (Neu5Gc, Neu5Ac); Neu5Gc-GD1a; Asialo-GM1 derivative; Gg4Cer(Neu5Gc, Neu5Ac); Glycolylneuraminic acid-containing GD1a
EINECS	Contact for details

Quality Control

Every batch of our (n-Acetylneuraminosyl-(2--8)-n-Glycolylneuraminic Acid)Gangliotetraosylceramide is manufactured and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated under an inert atmosphere. Allow the vial to reach room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in Chloroform/Methanol/Water mixtures

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.