Description

Uridine 5'-(o-2-Acetamido-2-Deoxymannopyranuronosyl Acid-(1--4)-2-Acetamide-2-Deoxyglucopyranosyl Diphosphate) is a complex, high-purity nucleotide sugar derivative critical for advanced biochemical research and synthesis. This compound serves as a key activated donor substrate in the enzymatic synthesis of glycosaminoglycans and other complex carbohydrate structures. It is primarily utilized by research institutions and pharmaceutical development teams focused on glycobiology, enzymology, and the development of novel therapeutic agents.

Application

• Enzymatic Glycosylation Studies: As a specialized nucleotide sugar donor for in vitro enzymatic synthesis of specific carbohydrate linkages.
• Glycobiology Research: Investigating the biosynthesis and function of glycosaminoglycans (GAGs) and other proteoglycans.
• Enzyme Characterization: Substrate for the assay and kinetic analysis of glycosyltransferases, particularly those involved in mannuronic acid transfer.
• Pharmaceutical R&D: Intermediate in the research and development of carbohydrate-based drugs, vaccines, and diagnostics.
• Biocatalyst Development: Used in the development and optimization of enzymatic pathways for the production of complex oligosaccharides.
• Metabolic Pathway Analysis: Tool for studying nucleotide sugar metabolism and its role in cellular processes and disease states.

Basic Information

Product Name	Uridine 5'-(o-2-Acetamido-2-Deoxymannopyranuronosyl Acid-(1--4)-2-Acetamide-2-Deoxyglucopyranosyl Diphosphate)
CAS No.	121324-56-9
Molecular Formula	C25H38N4O23P2
Molecular Weight	824.53 g/mol
Synonyms	UDP-2-Acetamido-2-deoxy-α-D-glucopyranuronosyl-(1→4)-2-acetamido-2-deoxy-α-D-glucopyranose; UDP-α-D-GlcNAcA-(1→4)-α-D-GlcNAc; UDP-GlcNAcA-GlcNAc; Uridine diphosphate N-acetylglucosaminuronic acid-(1,4)-N-acetylglucosamine; Uridine 5'-[2-(acetylamino)-2-deoxy-α-D-glucopyranuronosyl-(1→4)-2-(acetylamino)-2-deoxy-α-D-glucopyranosyl dihydrogen diphosphate]
EINECS	Contact for details

Quality Control

Our Uridine 5'-(o-2-Acetamido-2-Deoxymannopyranuronosyl Acid-(1--4)-2-Acetamide-2-Deoxyglucopyranosyl Diphosphate) is manufactured under controlled conditions to ensure the highest standards of purity and consistency. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, MS). Certificates of Analysis (COA) detailing all specifications are provided to guarantee product integrity for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated at -20°C. Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details
Biological Activity	Functional as glycosyl donor in enzymatic assays

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.