Description

1-Palmitoyl-2-(5-Oxovaleroyl)-Sn-Glycero-3-Phosphatidylcholine is a specialized, synthetic phospholipid derivative, specifically a phosphatidylcholine analog containing an oxovaleroyl (levulinyl) group at the sn-2 position. This compound matters as a high-purity biochemical tool and a key intermediate for advanced lipid research and pharmaceutical development. It is primarily needed by researchers and manufacturers in the fields of liposome formulation, drug delivery systems, and membrane biophysics, where precise lipid structures are critical for function.

Application

• Liposome and Lipid Nanoparticle (LNP) Research: A key component for constructing model membranes or drug delivery vesicles with specific surface properties.
• Pharmaceutical Intermediate: Used in the synthesis of more complex, functionalized phospholipids for targeted therapies.
• Biochemical Probe Development: The reactive ketone group (5-oxovaleroyl) allows for site-specific conjugation with ligands, dyes, or drugs via oxime or hydrazone chemistry.
• Membrane Protein Studies: Serves as a tailored lipid for reconstituting membrane proteins to study lipid-protein interactions.
• Reference Standard: Used as an analytical standard in lipidomics and quality control for lipid-based products.

Basic Information

Product Name	1-Palmitoyl-2-(5-Oxovaleroyl)-Sn-Glycero-3-Phosphatidylcholine
CAS No.	121324-31-0
Molecular Formula	C45H86NO10P
Molecular Weight	832.14 g/mol
Synonyms	1-Palmitoyl-2-levulinoyl-sn-glycero-3-phosphocholine; PC(16:0/5:0(4oxo)); Levulinoyl Phosphatidylcholine; 1-Hexadecanoyl-2-(4-oxopentanoyl)-sn-glycero-3-phosphocholine; OxoV-PC; PALMITOYL LEVULINOYL PHOSPHATIDYLCHOLINE; LysoPC(16:0/5:0(4oxo)); (2R)-2-[(4-Oxopentanoyl)oxy]-3-(palmitoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
EINECS	Contact for details

Quality Control

Our 1-Palmitoyl-2-(5-Oxovaleroyl)-Sn-Glycero-3-Phosphatidylcholine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or waxy solid
Identification (HPLC/MS)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.